Molecular Cell Biology
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Rsp5 promotes Gene Activation mediated by 9aaTAD Transcription Factors Oaf1 and Gal4
Nine-amino-acid transactivation domain, 9aaTAD, defines a large superfamily of yeast and mammals transcription factors. The transactivation of the 9aaTAD has been addressed to multiple general co-a…
Received 11 November 2009 23:04 UTC; Posted 16 November 2009
Posted to: Genetics & Genomics, Molecular Cell Biology
In Vitro Bactericidal Activities of Extracts From Ripe and Unripe Fruit of ‘Noni’
In an era of nutraceuticular research, ‘Noni’ fruit is considered as a panacea because of the profound claim on its medicinal uses in treating many diseases inclusive of infections of microbial ori…
Received 06 November 2009 05:30 UTC; Posted 09 November 2009
Posted to: Microbiology, Molecular Cell Biology
MicroDNAs and Transcriptional Regulation
Synthetic "microDNAs (MIDs)"is a new class of ~ 20-25 nucleotide-long DNAs capable of repressing the activity of the target gene at the level of transcription by mechanisms that have not …
Received 04 November 2009 08:33 UTC; Posted 04 November 2009
Posted to: Cancer, Genetics & Genomics, Molecular Cell Biology
Remarks on the number of tubulin dimers per neuron and implications for Hameroff-Penrose Orch OR
Stuart Hameroff has wrongly estimated that a typical brain neuron has 107 tubulin dimers and wrongly attributed this result to Yu and Baas, J. Neurosci. 1994; 14: 2818-2829. In this letter we sho…
Received 13 October 2009 09:35 UTC; Posted 14 October 2009
Posted to: Molecular Cell Biology, Neuroscience
Limusaurus and bird digit identity
Limusaurus is a remarkable herbivorous ceratosaur unique among theropods in having digits II, III and IV, with only a small metacarpal vestige of digit I. This raises interesting questions regard…
Received 06 October 2009 03:05 UTC; Posted 06 October 2009
Posted to: Developmental Biology, Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology
Mammalian cells in culture actively export specific microRNAs
The discovery of microRNAs (miRNAs) as a new class of regulators of gene expression has triggered an explosion of research, but has left many unanswered questions about how this regulation works an…
Received 04 September 2009 02:06 UTC; Posted 04 September 2009
Posted to: Molecular Cell Biology
Inhibition of Acid Phosphatase Enzyme Activity in the Presence of Noncrystalline Calcium Phosphate and Nanocrystalline Calcium Apatite: a Preliminary Study
BackgroundOur bones are remodelled repeatedly during life. A new and “healthy” bone tissue replaces the old one. Accordingly, the bone degrading cells, the osteoclasts, prefer old and fatigued …
Received 20 August 2009 11:52 UTC; Posted 20 August 2009
Posted to: Chemistry, Molecular Cell Biology
Multivalent ligands of CD22 for targeting of B cells
Multivalent ligands of CD22 for active targeting of B cells. Mary O’Reilly, Wei Hsu Chen, Gladys Completo, Ying Zeng, Satoshi Futakawa and Cory Rillahan and James C. Paulson, Departments of Chemica…
Received 04 August 2009 23:44 UTC; Posted 05 August 2009
Posted to: Biotechnology, Cancer, Chemistry, Immunology, Molecular Cell Biology
Can Vision Exist Without Somatosensation?
The interconnection between vision and somatosensation is already well-established and is further supplemented by the evolutionary link between eyes and photoreceptors, and the functional connectio…
Received 16 July 2009 14:23 UTC; Posted 17 July 2009
Posted to: Molecular Cell Biology, Neuroscience
Technical Note: The Use of RNA-interference as a Tool to Find Proteins Involved in Melanosome Formation or Transport
Melanosomes are lysosome-related organelles that produce and transport the pigment melanin within melanocytes. Mutations in proteins required for melanosome transport and formation lead to a range …
Received 10 July 2009 18:38 UTC; Posted 14 July 2009
Posted to: Molecular Cell Biology