Microbiology
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Prediction of Evolutionarily important catalytic amino acid of Mycobacterium tuberculosis O-Succinylbenzoate synthase through in silico mutational analysis
The emergence of tuberculosis resistant to multiple, first- and second-line antibiotics poses challenges to a global control strategy that relies on standard drug treatment regimens. The high drug-...
Received 17 September 2009 10:51 UTC; Posted 18 September 2009
Posted to: Biotechnology, Microbiology, Pharmacology, Bioinformatics
Pandemic (H1N1) 2009 Cluster Analysis: A Preliminary Assessment
Pandemic (H1N1) 2009 virus has been causing major concerns around the world because of its epidemic potential, rapid dissemination, rate of mutations, and the number of fatalities. One way to gain …
Received 16 September 2009 20:24 UTC; Posted 16 September 2009
Posted to: Genetics & Genomics, Microbiology, Bioinformatics
Application of a periodic table for the genetic code of the influenza A/H3N2 virus
The progress of life sciences would be greatly enhanced if biological data were available in a manner similar to the periodic table of the elements. Currently, the mutation rules for influenza viru…
Received 09 September 2009 15:17 UTC; Posted 09 September 2009
Posted to: Microbiology
Modeling, Simulation and Application of Bacterial Transduction in Genetic Algorithms
At present, all methods in Evolutionary Computation are bioinspired in the fundamental principles of neo-Darwinism as well as on a vertical gene transfer. Thus, on a mechanism in which an organism …
Received 08 September 2009 09:11 UTC; Posted 08 September 2009
Posted to: Microbiology, Bioinformatics, Evolutionary Biology
Computational binding mechanism of Mycobacterium tuberculosis UDP-NAG enolpyruvyl transferase (MurA) with inhibitors fosfomycin, cyclic disulfide analog RWJ-3981, pyrazolopyrimidine analog RWJ-110192, purine analog RWJ-140998, 5-sulfonoxy-anthranilic aci
Worldwide, tuberculosis (TB) remains the most frequent and important infectious disease causing morbidity and death. One-third of the world’s population is infected with Mycobacterium tuberculosis …
Received 08 September 2009 05:44 UTC; Posted 08 September 2009
Posted to: Biotechnology, Microbiology, Bioinformatics
Dating the cyanobacterial ancestor of the chloroplast
Cyanobacteria have played a pivotal role in the history of life on Earth being the first organism to carry out oxygenic photosynthesis, which changed atmospheric chemistry and allowed the evolution…
Received 28 August 2009 00:44 UTC; Posted 28 August 2009
Posted to: Ecology, Microbiology, Evolutionary Biology
Jellyfish as vectors of bacterial disease for farmed fish.
Gill diseases are common, especially in intensively reared fish; they result in respiratory distress, as well as impaired osmoregulation and excretion (1). Bacteria and parasites are common causes …
Received 17 August 2009 14:03 UTC; Posted 17 August 2009
Posted to: Microbiology, Earth & Environment
Modeling reaction-diffusion of molecules on surface and in volume spaces with the E-Cell System
The-Cell System is an advanced open-source simulation platform to model and analyze biochemical reaction networks. The present algorithm modules of the system assume that the reacting molecules are…
Received 31 July 2009 15:41 UTC; Posted 31 July 2009
Posted to: Developmental Biology, Microbiology, Bioinformatics
Modulation of the Nuclear Transcription Factor of Activated T Cells by Duck Hepatitis B Virus
During infection with hepadnaviruses besides the infectious agent a high number of subviral particles without nucleocapsids are produced, which are able to change the infection dramatically. In add…
Received 30 July 2009 08:42 UTC; Posted 30 July 2009
Posted to: Microbiology
Searching for better flu surveillance? A brief communication arising from Ginsberg et al. Nature 457, 1012-1014 (2009)
Through retrospectively analyzing billions of internet search queries, Ginsberg et al. identified a collection of specific searches that track the course of influenza-like illness (ILI) reported by…
Received 28 July 2009 19:16 UTC; Posted 05 August 2009
Posted to: Microbiology, Bioinformatics
