Immunology
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Breast Cancer Associated Metastasis is Significantly Increased in a Model of Autoimmune Arthritis
Chronic inflammation is known to play a role in cancer initiation, promotion,and metastasis. However, the mechanism by which inflammation promotes metastasis is still unclear. We evaluated if chron…
Received 10 December 2008 19:10 UTC; Posted 12 December 2008
Posted to: Cancer, Immunology
Parrot proventricular dilatation disease: a possible model of Guillain-Barré syndrome?
Proventricular Dilatation Disease (PDD) affects parrots with clinico-pathological aspects similar to those of the Guillain-Barré syndrome (GBS), a human neurophathy. We observed that in sera of PP…
Received 03 December 2008 10:30 UTC; Posted 03 December 2008
Posted to: Immunology
Competent intermediate hosts and genetic re-assortment: what does the ferret and raccoon model tell us about influenza pandemic risk?
Avian influenza virus (AI) strains such as H5N1 and H9N2 are endemic among birds and poultry globally and mainly within Eurasia. Human cases have been reported yet the transmission among humans has…
Received 12 November 2008 01:33 UTC; Posted 13 November 2008
Posted to: Genetics & Genomics, Immunology
Is the innate bio-protection power against human virus the same between males and females? A conclusion based on blood donor data of HTLV-I infection and case data of infectious diseases
Human T-cell leukemia virus type I (HTLV-I) is a retrovirus that causes adult T-cell leukemia. The male-to-female transmission is stronger than the reverse, so the carrier proportion of women is gr…
Received 24 October 2008 11:44 UTC; Posted 24 October 2008
Posted to: Cancer, Immunology, Microbiology
Steroidal anti inflammatory drug betamethasone significantly alters level of striatal dopamine in a rat model of Parkinson’s disease
Many scientific efforts have been well done to investigate the effects of anti inflammatory agents on the degenerative brain diseases such as Parkinson’s (PD) or Alzheimer’s disease and their affil…
Received 25 September 2008 20:10 UTC; Posted 26 September 2008
Posted to: Chemistry, Immunology, Neuroscience, Pharmacology
Dibutyltin Disrupts Glucocorticoid Receptor Function and Impairs Glucocorticoid-induced Suppression of Cytokine Production
Background. Organotins are highly toxic and widely distributed environmental chemicals. Dibutyltin (DBT) is used as stabilizer in the production of polyvinyl chloride plastics, and it is also the…
Received 18 September 2008 19:55 UTC; Posted 19 September 2008
Posted to: Immunology, Pharmacology, Bioinformatics
Simulations of Antigenic Variability in Influenza A
Computational models of the immune system (IS) and pathogenic agents have several applications, such as theory testing and validation, or as a complement to first stages of drug trials. One possibl…
Received 15 September 2008 00:15 UTC; Posted 15 September 2008
Posted to: Immunology, Bioinformatics
Pathogenetic role of tissue factor in graft-versus-host disease
Graft-versus-host disease (GVHD) is a serious complication after allogeneic stem cell transplantation, the mechanism of it is still not elucidated. Recent findings suggest that host endothelial cel…
Received 30 August 2008 03:15 UTC; Posted 01 September 2008
Posted to: Immunology, Molecular Cell Biology
Mutations in the SC4MOL gene encoding a novel methyl sterol oxidase cause autosomal recessive psoriasisiform dermatitis, microcephaly and developmental delay
Disorders of cholesterol biosynthesis have clinical manifestations involving skeleton, eyes, neurologic development, and skin. We describe a patient with congenital cataracts, developmental delay, ...
Received 06 August 2008 13:32 UTC; Posted 07 August 2008
Posted to: Genetics & Genomics, Immunology
Immunogenicity of human spermatozoa
Investigation and experimental design of the study was basically aimed at developing insight into the antigenicity of spermatozoa-associated proteins. Apart from studying the natural antigenicity o…
Received 25 June 2008 13:38 UTC; Posted 25 June 2008
Posted to: Immunology
