Immunology
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Female Scent Signals Enhances Male Resistance to Influenza
Scent of receptive females as signal to reproduction stimulate male mice to olfactory search of a potential breeding partner1, 2. This searching behavior is coupled with infection risk due to bac…
Received 03 June 2009 12:54 UTC; Posted 03 June 2009
Posted to: Ecology, Immunology
Spontaneous glomerular deposition of immunoglobulins for ACE (Angiotensin Converting Enzyme) induces spontaneous nephropathy in diabetogenic rats
We first discovered autoantibodies to ACE (angiotensin converting enzyme) in patients with type 2 diabetes mellitus1. The antibodies were positive for 64.5% of the patients with diabetes and were…
Received 23 May 2009 07:07 UTC; Posted 26 May 2009
Posted to: Immunology
Rethinking Leucine Zipper – a ubiquitous signal transduction motif
In this essay we attempt to reconsider the concept of the “Leucine Zipper” (LZ) protein oligomerization motif. Reasoning on the wealth of existing data, we suggest that despite of the structural si…
Received 22 May 2009 07:26 UTC; Posted 22 May 2009
Posted to: Cancer, Immunology, Molecular Cell Biology, Bioinformatics
Protective vaccination in the horse against Streptococcus equi with recombinant antigens
Streptococcus equi subspecies equi (S. equi) is a clonal, equine host-adapted pathogen of global importance that causes a highly contagious suppurative lymphodendopathy of the head and neck, ...
Received 26 March 2009 13:32 UTC; Posted 26 March 2009
Posted to: Immunology, Microbiology
Delayed-Type hypersensitivity to latex: Computational prediction of MHC class II epitopes on latex allergens
Delayed type hypersensitivity to natural rubber latex is rare compared to IgE mediated immediate reactions. Binding of allergens to MHC Class II is a crucial step in the presentation of antigens to…
Received 06 March 2009 10:17 UTC; Posted 06 March 2009
Posted to: Immunology, Bioinformatics
Cognitive epidemiology of ethnic health and the CHRM2 vagal vigour hypothesis
Ethnic populations representing areas throughout California were compared regarding cognitive ability, socioeconomic position, and mortality. Cognition and socioeconomic position were inversely cor…
Received 08 February 2009 01:47 UTC; Posted 18 February 2009
Posted to: Genetics & Genomics, Immunology, Neuroscience
Emergence and Fixing of Antiviral Resistance in Influenza A Via Recombination and Hitch Hiking
The dramatic rise of oseltamivir resistance in the H1N1 serotype in the 2007/2008 season and the fixing of H274Y in the 2008/2009 season has raised concerns regarding individuals at risk for season…
Received 29 January 2009 21:07 UTC; Posted 10 February 2009
Posted to: Biotechnology, Genetics & Genomics, Immunology
Hypercytokinemia: Increased or decreased innate immunity?
The adipose tissue is an active endocrine organ which secretes proinflammatory cytokines and chemokines resulting into raised serum levels. Hypercytokinemia has been interpreted as raised level of …
Received 23 December 2008 05:29 UTC; Posted 23 December 2008
Posted to: Ecology, Immunology
Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed…
Received 20 December 2008 03:31 UTC; Posted 23 December 2008
Posted to: Genetics & Genomics, Immunology
Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection
Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which…
Received 11 December 2008 16:24 UTC; Posted 15 December 2008
Posted to: Genetics & Genomics, Immunology, Microbiology
