Immunology
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Antibody responses to a Cryptosporidium parvum rCP15/60 vaccine
Cryptosporidium parvum is a zoonotic apicomplexa-protozoan pathogen that causes gastroenteritis and diarrhoea in mammals worldwide. The organism is transmitted by ingestion of oocysts, which are sh…
Received 20 November 2009 02:31 UTC; Posted 20 November 2009
Posted to: Immunology
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains
The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology an…
Received 21 October 2009 18:50 UTC; Posted 23 October 2009
Posted to: Genetics & Genomics, Immunology, Microbiology, Evolutionary Biology
Electron microscopy analysis of FcRγ localization after its capture by T cells by trogocytosis
T cells acquire various proteins from their cellular partners by the process of trogocytosis. We recently demonstrated that the FcγRIIIA receptor and its associated FcRγ are captured by T cells dur…
Received 02 October 2009 14:08 UTC; Posted 05 October 2009
Posted to: Immunology
New methods for analyzing serological data with applications to influenza surveillance
Two important challenges to the use of serological assays for influenza surveillance include the substantial amount of experimental effort involved, and the inherent noisiness of serological data. ...
Received 05 October 2009 08:10 UTC; Posted 05 October 2009
Posted to: Immunology, Evolutionary Biology
A novel strategy for the targeted analysis of protein and peptide metabolites
The detection and quantitation of exogenously administered biological macromolecules (e.g. vaccines, peptide and protein therapeutics) and their metabolites is frequently complicated by the presenc…
Received 29 September 2009 07:56 UTC; Posted 29 September 2009
Posted to: Biotechnology, Immunology, Pharmacology
Multivalent ligands of CD22 for targeting of B cells
Multivalent ligands of CD22 for active targeting of B cells. Mary O’Reilly, Wei Hsu Chen, Gladys Completo, Ying Zeng, Satoshi Futakawa and Cory Rillahan and James C. Paulson, Departments of Chemica…
Received 04 August 2009 23:44 UTC; Posted 05 August 2009
Posted to: Biotechnology, Cancer, Chemistry, Immunology, Molecular Cell Biology
Rescue with an anti-inflammatory peptide of chickens infected H5N1 avian flu
Chickens suffering from avian flu caused by H5N1 influenza virus are destined to die within 2 days due to a systemic inflammatory response. Since HVJ infection (1,2) and influenza virus infection (...
Received 14 July 2009 11:43 UTC; Posted 17 July 2009
Posted to: Immunology, Microbiology, Pharmacology
Cervical Cancer-Associated Human Papillomavirus 16 E7 Oncoprotein Inhibits Induction of Anti-Cancer Immunity by a CD4+ T Cell Dependent Mechanism
Attempts to develop therapeutic vaccines against cervical cancer have been proven difficult. One of the major causes of the failure is due to the use of the wrong mouse models based on transplantab…
Received 07 July 2009 04:20 UTC; Posted 08 July 2009
Posted to: Cancer, Immunology
Cyclin kinase inhibitor p21: a mediator of immune tolerance: direct and indirect evidence
Background: Uncontrolled proliferation of T-cells is considered a barrier to the induction of transplantation tolerance by T regulatory cells. Therefore, cyclin kinase inhibitor p21, one of the m…
Received 26 June 2009 19:29 UTC; Posted 29 June 2009
Posted to: Immunology
Varicella notification in immigrants: a brief report from Ferrara, Italy
Background and Aim of the work – We conducted a survey of varicella cases’ notifications in the immigrant population in the province of Ferrara, Italy.Materials and Methods – We collected notif…
Received 22 June 2009 07:09 UTC; Posted 22 June 2009
Posted to: Immunology, Microbiology
