Genetics & Genomics
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Signaling via Alk5 Controls Ontogeny of Lung Clara Cells
Clara cells, together with ciliated and pulmonary neuroendocrine cells, make up the epithelium of the bronchioles along the conducting airways. Clara cells are also known as Progenitor/Stem cells d…
Received 07 April 2009 18:29 UTC; Posted 08 April 2009
Posted to: Genetics & Genomics, Molecular Cell Biology
Evaluation of diversity, specialization, and gene specificity in transcriptomes
The transcriptome is a set of genes transcribed in a given tissue under specific conditions and can be characterized by a list of genes with their corresponding frequencies of transcription. Transc…
Received 31 March 2009 19:17 UTC; Posted 02 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Population genetic structure of the pelagic goby, Sufflogobius bibarbatus, in the Northern Benguela ecosystem, based on PCR-RFLP analysis of the mitochondrial control region and the ND 3 and 4 region (Dissertation).
Polymorphism within the mitochondrial NADH-3,4 dehydrogenase(ND-3/4) and control region (D-Loop) was studied by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysi…
Received 31 March 2009 04:17 UTC; Posted 31 March 2009
Posted to: Ecology, Genetics & Genomics, Evolutionary Biology
Biased amino acid composition in warm-blooded animals
Among eubacteria and archeabacteria, amino acid composition is correlated with habitat temperatures. In particular, species living at high temperatures have proteins enriched in the amino acids E-R…
Received 24 March 2009 16:39 UTC; Posted 25 March 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Assembling the Tree of Life in Europe (AToLE)
A network of scientists under the umbrella of ‘Assembling the Tree of Life in Europe (AToLE)’ seeks funding under the FP7-Theme: Cooperation – Environment (including Climate Change and Biodiversity…
Received 21 February 2009 10:19 UTC; Posted 26 February 2009
Posted to: Genetics & Genomics, Earth & Environment, Evolutionary Biology
The Necessity of Darwin
February 12th, 2009 was Charles Darwin’s 200th birthday, and November 2009 represents the 150th anniversary of the publication of his transformative book, The Origin of Species. It seems a good tim…
Received 19 February 2009 10:12 UTC; Posted 23 February 2009
Posted to: Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology
Evolutionary descent of prion genes from a ZIP metal ion transport ancestor
In the more than 20 years since its discovery, both the phylogenetic origin and cellular function of the prion protein (PrP) have remained enigmatic. Insights into the function of PrP may be obtain…
Received 10 February 2009 21:16 UTC; Posted 10 February 2009
Posted to: Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology
Genome-wide association study identifies FUT8 and ESR2 as co-regulators of a bi-antennary N-linked glycan A2 (GlcNAc2Man3GlcNAc2) in human plasma proteins
HPLC analysis of N-glycans quantified levels of the biantennary glycan (A2) in plasma proteins of 924 individuals. Subsequent genome-wide association study (GWAS) using 317,503 single nucleotide po…
Received 10 February 2009 02:55 UTC; Posted 10 February 2009
Posted to: Genetics & Genomics, Molecular Cell Biology
Cognitive epidemiology of ethnic health and the CHRM2 vagal vigour hypothesis
Ethnic populations representing areas throughout California were compared regarding cognitive ability, socioeconomic position, and mortality. Cognition and socioeconomic position were inversely cor…
Received 08 February 2009 01:47 UTC; Posted 18 February 2009
Posted to: Genetics & Genomics, Immunology, Neuroscience
Activation of an Estrogen/ Estrogen Receptor Signaling by BIG3 Through Its Inhibitory Effect on Nuclear Transport of PHB2/REA in Breast Cancer
Breast cancer is known to be a hormone-dependent disease, and estrogens through an interaction with estrogen receptor (ER) enhance the proliferative and metastatic activity of breast tumor cells. H…
Received 30 January 2009 04:54 UTC; Posted 30 January 2009
Posted to: Cancer, Genetics & Genomics