Genetics & Genomics
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Systems level analysis of transgenerational spermatogenic inheritance predicts biomarkers and underlying pathways
Transgenerational spermatogenic inheritance of adult male acquired CNS gene expression characteristics has recently been discovered using a Drosophila systems model. In this novel mode of inheritan…
Received 03 June 2009 14:08 UTC; Posted 05 June 2009
Posted to: Genetics & Genomics
Structural Analysis of Polarizing Indels Argues the Root of the Tree of Life is Near the Chloroflexi
Determining which branches of the tree of life have derived features narrows down the possible location of the root. Currently the polarization of indels done by Lake et al.1-5 and the polarizi…
Received 26 May 2009 18:04 UTC; Posted 27 May 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Why are Male IQ Scores More Variable?
The male female difference in the variance of quantitative traits including IQ can be accounted for by the observation of the concentration of genes involved in brain development on the X chromosom…
Received 12 May 2009 01:32 UTC; Posted 12 May 2009
Posted to: Genetics & Genomics
Reflect: Augmented Browsing for the Life Scientist
Anyone who regularly reads life science literature often comes across names of genes, proteins, or small molecules that they would like to know more about. To make this process easier, we have deve…
Received 02 May 2009 01:44 UTC; Posted 04 May 2009
Posted to: Biotechnology, Chemistry, Genetics & Genomics, Molecular Cell Biology, Bioinformatics
Androgen Receptor and Vasopressin Receptor (AVPR1a) Genetic Polymorphisms are not associated with Marital Status or Fertility among Ariaal Men of Northern Kenya
A growing body of scholarship implicates testosterone and vasopressin in male reproductive behavior, including in humans. Since hormones exert their effects through their respective receptors, an o…
Received 30 April 2009 23:27 UTC; Posted 01 May 2009
Posted to: Genetics & Genomics
MitoWheel, visualizing the human mitochondrial genome
So far researchers, web users were restricted to non-intuitive and visually poor text based databases every time they wanted to take a look on the mitochondrial DNA and find a region of interest. B…
Received 07 May 2009 14:40 UTC; Posted 07 May 2009
Posted to: Genetics & Genomics, Bioinformatics
DNA sequences classification and computation scheme based on the symmetry principle
The DNA sequences containing multifarious novel symmetrical structure frequently play crucial role in how genomes work. Here we present a new scheme for understanding the structural features and po…
Received 21 April 2009 14:18 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Parallel routes of human carcinoma development: Implications of the age-specific incidence data
The multi-stage hypothesis suggests that cancers develop through a single defined series of genetic alterations. This hypothesis was first suggested over 50 years ago based upon age-specific incide…
Received 17 April 2009 18:14 UTC; Posted 17 April 2009
Posted to: Cancer, Genetics & Genomics
Delving into Vertebrate Serpins for Understanding their Evolution
The superfamily of serine proteinase inhibitors (serpins) is involved in an array of fundamental biological processes such as blood coagulation, cell differentiation, cell migration, complement act…
Received 16 April 2009 17:02 UTC; Posted 16 April 2009
Posted to: Genetics & Genomics, Evolutionary Biology
Dogs Never Gets Prion Diseases. The Entropic Landscape Analysis of Prion Proteins Answers Why.
The Entropic Landscape Analysis was applied to the prion protein sequences of various mammals in order to detect potential sites of variants that would be responsible for the susceptibility of prio…
Received 08 April 2009 10:27 UTC; Posted 09 April 2009
Posted to: Genetics & Genomics, Neuroscience, Bioinformatics, Evolutionary Biology
