Genetics & Genomics
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Limusaurus and bird digit identity
Limusaurus is a remarkable herbivorous ceratosaur unique among theropods in having digits II, III and IV, with only a small metacarpal vestige of digit I. This raises interesting questions regard…
Received 06 October 2009 03:05 UTC; Posted 06 October 2009
Posted to: Developmental Biology, Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology
Variation in PNPLA3 is associated with outcomes in alcoholic liver disease
Two recent genome-wide association studies have described associations of SNP variants in PNPLA3 with nonalcoholic fatty liver and plasma liver enzyme levels in population based cohorts. We inves…
Received 05 October 2009 19:14 UTC; Posted 06 October 2009
Posted to: Genetics & Genomics
Nuclear DNA and protein content evaluation in Taxus plant cell cultures using multiparameter flow cytometry
Plant cell cultures of Taxus provide the most reliable production methods for the anti-cancer drug paclitaxel. In order to comprehend the inherent culture heterogeneity and production variability i…
Received 28 September 2009 22:50 UTC; Posted 01 October 2009
Posted to: Biotechnology, Cancer, Developmental Biology, Genetics & Genomics, Plant Biology
Interspecific differences in single nucleotide polymorphisms (SNPs) and indels in expressed sequence tag libraries of oil palm Elaeis guineensis and E. oleifera
Oil palm is the second largest source of edible oil, which meets one-fifth of global demands of oils and fats. Expressed sequence tag (EST) sequencing programs have provided a wealth of information…
Received 24 September 2009 05:38 UTC; Posted 24 September 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Pandemic (H1N1) 2009 Cluster Analysis: A Preliminary Assessment
Pandemic (H1N1) 2009 virus has been causing major concerns around the world because of its epidemic potential, rapid dissemination, rate of mutations, and the number of fatalities. One way to gain …
Received 16 September 2009 20:24 UTC; Posted 16 September 2009
Posted to: Genetics & Genomics, Microbiology, Bioinformatics
Novel determinants describe chaperonin substrate proteins
Molecular chaperones ensure that their substrate proteins reach the functional native state and prevent their aggregation. The bacterial GroEL/ES chaperonin system is understood in great detail on …
Received 15 September 2009 12:00 UTC; Posted 15 September 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Frequency-dependent selection predicts patterns of radiations and biodiversity
Most empirical studies support a decline in speciation rates through time, although evidence for constant speciation rates also exists. Declining rates have been explained by invoking niche-filling…
Received 12 September 2009 05:41 UTC; Posted 14 September 2009
Posted to: Ecology, Genetics & Genomics, Bioinformatics, Earth & Environment, Evolutionary Biology
Polymorphisms of TSER and MTHFR are associated with prognosis of fluoropyrimidine-based therapy in colorectal cancer patients
This study was designed to investigate the influence of TSER and MTHFR polymorphisms on the clinical outcomes of patients with colorectal cancer receiving 5-FU-based chemotherapy. Genomic DNA was i…
Received 11 September 2009 00:36 UTC; Posted 11 September 2009
Posted to: Cancer, Genetics & Genomics
In silico microRNA identification from paprika (Capsicum annuum) ESTs
A total of 33,311 Expressed Sequence Tags (EST) of paprika were mined from the GenBank EST database. The redundancy of the EST sequences was removed using CAP3 and it resulted 4,541 contigs 8,539 s…
Received 24 September 2009 05:19 UTC; Posted 24 September 2009
Posted to: Genetics & Genomics, Bioinformatics, Plant Biology
MUEGANO: A divide and conquer algorithm to overcome memory limitations when assembling shotgun projects
When assembling a large quantity of reads in a genomic shotgun project a serious limitation is the amount of random access memory (RAM) of the computers used in the project. This arises because all…
Received 02 September 2009 14:58 UTC; Posted 02 September 2009
Posted to: Genetics & Genomics, Bioinformatics
