Genetics & Genomics
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Design of a dynamic model of genes with multiple autonomous regulatory modules by evolution in silico
A new approach to design a dynamic model of genes with multiple autonomous regulatory modules by evolution in silico is proposed. The approach is based on Genetic Algorithms, with new crossover ope…
Received 29 October 2009 00:50 UTC; Posted 29 October 2009
Posted to: Biotechnology, Developmental Biology, Genetics & Genomics, Bioinformatics, Evolutionary Biology
The Role of Neuregulin 1 in Schizophrenia: A Bioinformatics Approach
Context: Notwithstanding the great number of studies on the etiology and pathophysiology of schizophrenia, both issues remain far from being fully understood. Schizophrenia seems to be related to…
Received 27 October 2009 21:54 UTC; Posted 28 October 2009
Posted to: Genetics & Genomics, Neuroscience, Bioinformatics
BRAGOMAP – a new Perl script for high throughoutput blast results analysis including GO and MapMan automatic annotations
Analyzing of sequences similarities is the first and most important method used to find out the function of unknown nucleotides. Searching of homologs should be done carefully not to loose any impo…
Received 25 October 2009 19:49 UTC; Posted 26 October 2009
Posted to: Genetics & Genomics, Bioinformatics, Plant Biology
Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD).
Although there is evidence for the involvement of genes of serotonergic and dopaminergic systems in the manifestation of the Behavioural and Psychological Symptoms in Dementia (BPSD), genetic assoc…
Received 23 October 2009 20:37 UTC; Posted 26 October 2009
Posted to: Genetics & Genomics, Neuroscience
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains
The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology an…
Received 21 October 2009 18:50 UTC; Posted 23 October 2009
Posted to: Genetics & Genomics, Immunology, Microbiology, Evolutionary Biology
The Origin and Evolution of Viruses as Molecular Organisms
Viruses are the most abundant life forms and the repertoire of viral genes is greater than that of cellular genes. It is also evident that viruses have played a major role in driving cellular evolu…
Received 21 October 2009 18:19 UTC; Posted 23 October 2009
Posted to: Genetics & Genomics, Microbiology, Evolutionary Biology
Chromosomal mutational algebra: a new algebra to manipulate chromosomal mutation
This study leads to a new algebra. An algebra is defined on the common mechanisms of chromosomal mutation. The algebra (SΨ(C), *, ’, Δ, D) is constructed for a given C and Ψ...
Received 20 October 2009 03:43 UTC; Posted 20 October 2009
Posted to: Genetics & Genomics, Bioinformatics
Towards a genome-wide transcriptogram: the Saccharomyces cerevisiae case
A genome modular classification that associates cellular processes to modules could lead to a method to quantify the differences in gene expression levels in different cellular stages or conditions…
Received 16 October 2009 15:38 UTC; Posted 19 October 2009
Posted to: Biotechnology, Genetics & Genomics, Bioinformatics
Genome-scale approach proves that the lungfish-coelacanth sister group is the closest living relative of tetrapods with the BEST program
The origin of tetrapods has not been resolved for decades. Three principal hypotheses (lungfish-tetrapod, coelacanth-tetrapod, or lungfish-coelacanth sister group) have been proposed. We used the B…
Received 15 October 2009 04:03 UTC; Posted 15 October 2009
Posted to: Ecology, Genetics & Genomics, Bioinformatics, Evolutionary Biology
Mega- change gene copies are produced by reverse transcription of precursor RNA with replaced introns.
This report describes the presence of copy genes in plants where the sequence similarity to their parental genes is almost completely limited to limited to the exons. Evidence is presented that ind…
Received 07 October 2009 15:02 UTC; Posted 07 October 2009
Posted to: Genetics & Genomics, Bioinformatics, Plant Biology, Evolutionary Biology