Developmental Biology
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Frizzled Proteins are bona fide G Protein-Coupled Receptors
Receptors of the Frizzled family initiate Wnt ligand-dependent signaling controllingmultiple steps in organism development and highly conserved in evolution.Misactivation of the Wnt/Frizzled si…
Received 08 January 2009 16:38 UTC; Posted 09 January 2009
Posted to: Cancer, Developmental Biology, Molecular Cell Biology, Pharmacology
Evolution of Thriftiness: An analytical viewpoint
We examine here, using a simple mathematical model, the conditions under which thrifty genes or fetal programming could evolve. Obesity and related disorders are thought to have their roots in meta…
Received 23 December 2008 05:09 UTC; Posted 23 December 2008
Posted to: Developmental Biology, Evolutionary Biology
Money handling influences BMI: a survey of cashiers
Money is a recent phenomenon in the evolutionary history of man and therefore no separate brain centre to handle money is likely to have evolved. The brain areas activated by food reward and money …
Received 22 December 2008 04:51 UTC; Posted 22 December 2008
Posted to: Developmental Biology, Ecology, Neuroscience
Kinetic control of eukaryotic chromatin structure by recursive topological restraints
Chromatin structure undergoes many changes during the cell cycle and in response to regulatory events. A basic unit of chromatin organization is the nucleosome core particle. However, very little i…
Received 17 December 2008 18:09 UTC; Posted 18 December 2008
Posted to: Developmental Biology, Genetics & Genomics, Molecular Cell Biology
Trophoblastic hormones direct early human embryogenesis
Division of the human zygote leads to the formation of the blastocyst that contains human embryonic stem cells (hESC) which develop into the embryo. Little is known about the physiological signals…
Received 16 December 2008 20:58 UTC; Posted 20 December 2008
Posted to: Developmental Biology, Neuroscience
Estimating body Mass and Nutritional Status from Subadult Hominin Skeletons
Hominin body size and shape are key components to reconstructing phylogeny, life history, adaptation, and behavior in ancestral populations1. For adults, geometric properties of the femoral midsh…
Received 04 November 2008 19:29 UTC; Posted 07 November 2008
Posted to: Developmental Biology, Evolutionary Biology
Human metabolic adaptations and prolonged expensive neurodevelopment: A review
1. After weaning, human hunter-gatherer juveniles receive substantial (≈3.5-7 MJ day-1), extended (≈15 years) and reliable (kin and nonkin food pooling) energy provision.2. The childhood (pedia…
Received 30 October 2008 03:54 UTC; Posted 31 October 2008
Posted to: Developmental Biology, Neuroscience, Evolutionary Biology
Evidence of salt secretion at the stem of Melaleuca cuticularis Labill.
It has been observed that Melaleuca cuticularis Labill. has the ability to secrete salt solution to the surface of its stem. No literature has been found to illustrate other species’ capacity to …
Received 30 October 2008 01:49 UTC; Posted 31 October 2008
Posted to: Developmental Biology, Earth & Environment, Plant Biology
Where did Words Come from? A Linking Theory of Sound Symbolism and Natural Language Evolution
Where did words come from? The traditional view is that the relation between the sound of a word and its meaning is arbitrary. An alternative hypothesis, known as sound symbolism, holds that form-m…
Received 06 October 2008 00:21 UTC; Posted 06 October 2008
Posted to: Developmental Biology, Ecology, Neuroscience
A bizarre Jurassic maniraptoran from China with elongate ribbon-like feathers
Recent coelurosaurian discoveries have greatly enriched our knowledge of the dinosaur-bird transition, but all reported taxa close to this transition are from relatively well-known coelurosaurian g…
Received 24 September 2008 12:52 UTC; Posted 24 September 2008
Posted to: Developmental Biology, Ecology, Earth & Environment