Chemistry
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Early Life Relict Feature in Peptide Mass Distribution
Molecular mass of a biomolecule is characterized in mass spectroscopy by the monoisitopic mass Mmono and the average isotopic mass Mav. We found that peptide masses mapped on a plane made by tw…
Received 16 October 2008 15:46 UTC; Posted 17 October 2008
Posted to: Chemistry, Evolutionary Biology
Facile Synthesis and Versatilities of Polyanthraquinoylamine Nanofibril Bundles with Self Stability and High Carbon Yield
A facile synthesis for nanosized conducting polymers with inherent self-stability and multi-functionalities is a main challenge. Here we simply synthesize intrinsically self-stabilized nanofibril b…
Received 14 October 2008 11:11 UTC; Posted 15 October 2008
Posted to: Biotechnology, Chemistry
Carbon-driven Chemical Interactions between Alumina and Iron: A possible reaction pathway in Earth’s interior
Seismological and geochemical observations have revealed a complex structure for the earth’s core-mantle boundary (CMB) region, with lateral and chemical heterogeneities. The presence of higher tha…
Received 29 September 2008 05:12 UTC; Posted 29 September 2008
Posted to: Chemistry, Earth & Environment
Steroidal anti inflammatory drug betamethasone significantly alters level of striatal dopamine in a rat model of Parkinson’s disease
Many scientific efforts have been well done to investigate the effects of anti inflammatory agents on the degenerative brain diseases such as Parkinson’s (PD) or Alzheimer’s disease and their affil…
Received 25 September 2008 20:10 UTC; Posted 26 September 2008
Posted to: Chemistry, Immunology, Neuroscience, Pharmacology
GO faster ChEBI with Reasonable Biochemistry
Chemical Entities of Biological Interest (ChEBI) is a database and ontology that represents biochemical knowledge about small molecules. Recent changes to the ontology have created new opportunitie…
Received 25 September 2008 16:37 UTC; Posted 25 September 2008
Posted to: Biotechnology, Chemistry, Bioinformatics
Experiment study on Ma-Xing-Shi-Gan-Tang (MXSGT) and its decomposed recipes on anti-influenza virus A
Ancient China was an East Asian country with large population. As we review the history of China, large scale epidemic like Black Death in Europe rarely occurs. It can be seen that the Traditional …
Received 05 September 2008 10:47 UTC; Posted 08 September 2008
Posted to: Chemistry
Validated, Ultra Violet Spectroscopy method for the Dissolution study of Mycophenolate mofetil immediate release 500mg tablets
A simple, selective and precise dissolution method was developed and validated for the Mycophenolate mofetil immediate release tablets. The method employed dissolution medium 0.1N HCl (pH1.2) and v…
Received 01 September 2008 11:20 UTC; Posted 03 September 2008
Posted to: Chemistry, Pharmacology
Optimization of the Ugi reaction using parallel synthesis and automated liquid handling
The Ugi reaction has proved to be a convenient way to quickly create diverse libraries of compounds. It involves the reaction of an amine, an aldehyde, a carboxylic acid and an isonitrile typically…
Received 27 August 2008 20:56 UTC; Posted 29 August 2008
Posted to: Chemistry, Pharmacology
Open Notebook Science – Falcipain-2 Preliminary Results
This talk was presented by Jean-Claude Bradley at the American Chemical Society meeting in Philadelphia on August 20, 2008. An introduction to Open Notebook Science is presented followed by an illu…
Received 26 August 2008 09:45 UTC; Posted 26 August 2008
Posted to: Chemistry, Bioinformatics
Secondary water pore formation for proton transport in a ClC exchanger revealed by an atomistic molecular dynamics simulation
Several prokaryotic ClC proteins have been demonstrated to function as exchangers that transport both chloride ions and protons simultaneously in opposite directions. However, the path of the proto…
Received 07 August 2008 07:41 UTC; Posted 15 August 2008
Posted to: Biotechnology, Chemistry
