Chemistry
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Multivalent ligands of CD22 for targeting of B cells
Multivalent ligands of CD22 for active targeting of B cells. Mary O’Reilly, Wei Hsu Chen, Gladys Completo, Ying Zeng, Satoshi Futakawa and Cory Rillahan and James C. Paulson, Departments of Chemica…
Received 04 August 2009 23:44 UTC; Posted 05 August 2009
Posted to: Biotechnology, Cancer, Chemistry, Immunology, Molecular Cell Biology
Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16α-hydroxylation by Cytochrome P450-2C11. Docking stu…
Received 03 August 2009 05:39 UTC; Posted 03 August 2009
Posted to: Chemistry, Bioinformatics
Absolute Aqueous Redox Potentials ( via a new link between aqueous and gaseous properties)
The new finding here, that the conventional standard potentials (based on S.H.E.) are linearly dependent on ionization potentials, has yielded the absolute values of aqueous standard potentials.
Received 03 July 2009 12:57 UTC; Posted 06 July 2009
Posted to: Chemistry
Sugar-based synthesis of Tamiflu and its inhibitory effects on cell secretion
Tamiflu is currently the most effective drug for the treatment of influenza. But the unmet supply and side effects of this drug demand urgent solutions. In this article, a practical synthesis of Ta…
Received 19 June 2009 16:47 UTC; Posted 22 June 2009
Posted to: Chemistry, Molecular Cell Biology
Congener specific organic carbon normalized soil and sediment-water partitioning coefficients for the C1 through C8 perfluoroalkyl carboxylic and sulfonic acids
Organic carbon normalized soil and sediment-water partitioning coefficients (Koc) were estimated for all C1 through C8 perfluoroalkyl carboxylic (PFCA) and sulfonic (PFSA) acid congeners. The…
Received 06 June 2009 02:02 UTC; Posted 08 June 2009
Posted to: Chemistry, Earth & Environment
Sulfur-bound biomarkers of a Monterey shale and a Greenland lake sediment
Seeking to reconstruct the biogeochemical processes that produced organic sulfur compounds in two unique depositional environments, we used the nickel boride desulfurization reaction to release hyd…
Received 05 June 2009 02:05 UTC; Posted 05 June 2009
Posted to: Chemistry, Ecology, Earth & Environment
A comparative assessment of octanol-water partitioning and distribution constant estimation methods for perfluoroalkyl carboxylates and sulfonates
New experimental data is available in the literature regarding the octanol-water distribution behavior of representative straight chain perfluoroalkyl carboxylate (PFCA) and sulfonate (PFSA) congen…
Received 29 May 2009 05:45 UTC; Posted 01 June 2009
Posted to: Chemistry, Earth & Environment
Atomic Structures of Molecules Based on Additivity of Atomic and/or Ionic Radii
The authors have shown in recent years that interatomic and interionic distances are sums of the radii of the adjacent atoms and/or ions. Many examples will be provided and it will be shown how the…
Received 28 May 2009 09:26 UTC; Posted 03 June 2009
Posted to: Chemistry
First Hematological Signals of Latent Anemia to Aging Population
Anemia is an independent risk factor for morbidity and mortality in an array of disorders common to seniors including cancer, renal diseases and heart diseases. The aim of this study was to identi…
Received 26 May 2009 08:32 UTC; Posted 26 May 2009
Posted to: Chemistry
An assessment of organic solvent based equilibrium partitioning methods for predicting the bioconcentration behavior of perfluorinated sulfonic acids, carboxylic acids, and sulfonamides
SPARC, KOWWIN, and ALOGPS octanol-water partitioning (log Kow) and distribution (log D) constants were calculated for all C1 through C8 and the straight chain C9 through C15 perfluoroalky…
Received 16 May 2009 02:26 UTC; Posted 18 May 2009
Posted to: Chemistry, Earth & Environment
