Cancer
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Breast Cancer Associated Metastasis is Significantly Increased in a Model of Autoimmune Arthritis
Chronic inflammation is known to play a role in cancer initiation, promotion,and metastasis. However, the mechanism by which inflammation promotes metastasis is still unclear. We evaluated if chron…
Received 10 December 2008 19:10 UTC; Posted 12 December 2008
Posted to: Cancer, Immunology
Adenovirus-mediated transfer of siRNA against survivin enhances the radiosensitivity of human non-small cell lung cancer cells
Expression of survivin has been reported to be correlated with shorter survival in patients with non-small cell lung cancer (NSCLC), and overexpression of survivin may lead to radioresistance in va…
Received 01 December 2008 17:22 UTC; Posted 02 December 2008
Posted to: Cancer, Molecular Cell Biology
A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes
A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our …
Received 24 November 2008 07:11 UTC; Posted 24 November 2008
Posted to: Cancer, Genetics & Genomics
Fracture Toughness of Human Solid Cancers
Human solid cancers typically are harder and firmer than surrounding normal tissue upon clinical palpation. This characteristic has been linked to the presence of abundant collagen in the tumor str…
Received 02 November 2008 22:42 UTC; Posted 10 November 2008
Posted to: Biotechnology, Cancer
Is the innate bio-protection power against human virus the same between males and females? A conclusion based on blood donor data of HTLV-I infection and case data of infectious diseases
Human T-cell leukemia virus type I (HTLV-I) is a retrovirus that causes adult T-cell leukemia. The male-to-female transmission is stronger than the reverse, so the carrier proportion of women is gr…
Received 24 October 2008 11:44 UTC; Posted 24 October 2008
Posted to: Cancer, Immunology, Microbiology
The monoclonal antibody nBT062 conjugated to maytansinoids has potent and selective cytotoxicity against CD138 positive multiple myeloma cells in vitro and in vivo
CD138 (Syndecan1) is highly expressed on multiple myeloma (MM) cells. In this study, we examined the anti-MM effect of murine/human chimeric CD138-specific monoclonal antibody (mAb) nBT062 conjugat…
Received 07 October 2008 22:33 UTC; Posted 08 October 2008
Posted to: Cancer, Molecular Cell Biology
First reports of computed tomographic colonography for the screening of colorectal polyps in acromegalic patients
Aim: To analyze the CTC performance for the screening of colorectal polyps in acromegalic patients. Materials and Methods: A prospective study of 21 acromegalic patients, 12 male and 9 fem…
Received 23 September 2008 00:49 UTC; Posted 24 September 2008
Posted to: Biotechnology, Cancer
Off-target response to decoy oligodeoxynucleotide treatment
Background: The transcription factor PAX2 regulates key developmental processes, including mediation of resistance to apoptosis. Inappropriate PAX2 expression has been implicated in facilitating …
Received 10 September 2008 04:24 UTC; Posted 10 September 2008
Posted to: Cancer, Developmental Biology, Molecular Cell Biology
Efficient polyethylenimine-mediated gene delivery proceeds via a caveolar pathway in HeLa cells.
Most in vivo gene therapies will require cell-specific targeting. Although vector targeting through ligand attachment has met with success in generating gene delivery particles that are capable of …
Received 05 September 2008 17:33 UTC; Posted 08 September 2008
Posted to: Biotechnology, Cancer
Detection of Stomach Cancer by TV-Endoscope Colour Enhancement Image Processing
Using modern TV-endoscope equipment, we have experimented image processing in several ways. This time, we designed new image processing unit called “Color Subtracted Enhancement image processing u…
Received 04 September 2008 14:01 UTC; Posted 08 September 2008
Posted to: Cancer
