Cancer
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Carrier cell-mediated cell lysis of squamous cell carcinoma by squamous cell carcinoma antigen 1 promoter-driven oncolytic adenovirus
The squamous cell carcinoma antigen (SCCA) serves as a serological marker for squamous cell carcinomas. Molecular cloning of the SCCA genomic region has revealed the presence of two tandemly arraye…
Received 02 May 2009 09:34 UTC; Posted 08 May 2009
Posted to: Cancer
Enhanced anti-cancer activity of microglia by AAV2-mediated IL-12 in the therapy of glioblastoma multiforme
Microglia has been found to diversify its function by cancerous cells or in a cancerous environment, thereby contributing to cancer growth and metastasis. Its immuno-activity, however, can be modul…
Received 20 April 2009 10:50 UTC; Posted 24 April 2009
Posted to: Cancer
Parallel routes of human carcinoma development: Implications of the age-specific incidence data
The multi-stage hypothesis suggests that cancers develop through a single defined series of genetic alterations. This hypothesis was first suggested over 50 years ago based upon age-specific incide…
Received 17 April 2009 18:14 UTC; Posted 17 April 2009
Posted to: Cancer, Genetics & Genomics
Talin1 Promotes Prostate Cancer Invasion and Metastasis via AKT Signaling and Anoikis Resistance
Talin1 is an integrin regulatory protein that mediates integrin interactions with the extracellular matrix (ECM). This study investigated the significance of talin1 in prostate cancer progression t…
Received 10 April 2009 19:18 UTC; Posted 14 April 2009
Posted to: Cancer
A Therapeutically Relevant Difference in Leukemia and Normal Stem Cell Self Renewal
Abnormal self-renewal and differentiation are defining features of acute myeloid leukemia (AML). Using models of hematopoiesis, we show that persistent self-renewal that ignores differentiation si…
Received 08 April 2009 20:19 UTC; Posted 09 April 2009
Posted to: Cancer
Adherence to cancer screenings: Is the telephone survey a good method of investigation?
INTRODUCTION – In order to define subjective variables, the methodology on the assessment of the women participation to screening programs to prevent cervical cancer is presented.*MATERIALS AND…
Received 01 April 2009 12:08 UTC; Posted 01 April 2009
Posted to: Cancer
Spontaneous development of gastric tumors in mice devoid of suppressor of cytokine signaling-3 in the gastrointestinal epithelium
Constitutive activation of the signal transducer and activator of transcription-3 (STAT3) has been reported in epithelial tumors. SOCS3 is a potential negative feedback regulator of STAT3; however,...
Received 01 April 2009 02:08 UTC; Posted 01 April 2009
Posted to: Cancer
Seasonal patterns of presentation in primary malignant brain tumors and metastases based on a retrospective neuropathologic database
Seasonal variation in the occurrence of several classes of cancer has been observed in the past. However, evidence for such trends in adult central nervous system tumors is scant. We have analyzed …
Received 24 March 2009 03:23 UTC; Posted 24 March 2009
Posted to: Cancer, Neuroscience, Earth & Environment
Far-infrared rays control prostate cancer cells in vitro and in vivo
We introduce a new effective method to control hormone refractory prostate cancer cells by using an activated rubber/resin form (RB), far-infrared ray emitter, with or without sodium butyrate (SB)....
Received 20 March 2009 07:15 UTC; Posted 20 March 2009
Posted to: Cancer
A new mathematical model for radiation cell killing mechanism: Target cumulating model
There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly. The more adva…
Received 18 February 2009 11:40 UTC; Posted 18 February 2009
Posted to: Cancer
