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Multivalent ligands of CD22 for targeting of B cells
Multivalent ligands of CD22 for active targeting of B cells. Mary O’Reilly, Wei Hsu Chen, Gladys Completo, Ying Zeng, Satoshi Futakawa and Cory Rillahan and James C. Paulson, Departments of Chemica…
Received 04 August 2009 23:44 UTC; Posted 05 August 2009
Posted to: Biotechnology, Cancer, Chemistry, Immunology, Molecular Cell Biology
Quantitative MRI and MR Spectroscopy of Multiple Sclerosis, Alzheimer’s Disease, Epilepsy and Cancer Microimaging Techniques
Clinical MRI and MRS have promise in molecular imaging. Microimaging techniques offer a promising research tool to get noninvasive data in monitoring the effect of drugs.
Received 01 August 2009 17:17 UTC; Posted 03 August 2009
Posted to: Biotechnology, Cancer, Neuroscience
Magnetic Resonance imaging (MRI) in detection of Bifidobacterium longum and Clostridium novyi-NT labeled with superparamagnetic iron oxide (SPIO) nanoparticle
Purpose: To investigate the MR imaging of Bifidobacterium longum and Clostridium novyi-NT labeling with superparamagnetic iron oxide (SPIO) nanoparticles.Materials and methods: Tubes co…
Received 16 July 2009 08:25 UTC; Posted 22 July 2009
Posted to: Biotechnology, Cancer, Microbiology
The History, Development and Impact of Computed Imaging in Neurological Diagnosis and Neurosurgery: CT, MRI, and DTI
A steady series of advances in physics, mathematics, computers and clinical imaging science have progressively transformed diagnosis and treatment of neurological and neurosurgical disorders in the…
Received 12 July 2009 06:43 UTC; Posted 13 July 2009
Posted to: Biotechnology, Cancer, Neuroscience
Cervical Cancer-Associated Human Papillomavirus 16 E7 Oncoprotein Inhibits Induction of Anti-Cancer Immunity by a CD4+ T Cell Dependent Mechanism
Attempts to develop therapeutic vaccines against cervical cancer have been proven difficult. One of the major causes of the failure is due to the use of the wrong mouse models based on transplantab…
Received 07 July 2009 04:20 UTC; Posted 08 July 2009
Posted to: Cancer, Immunology
Independent elaboration of steroid hormone signaling pathways in Metazoans
Steroid hormones regulate many physiological processes in vertebrates, nematodes and arthropods through binding to nuclear receptors (NR), a metazoan-specific family of ligand-activated transcripti…
Received 25 June 2009 20:55 UTC; Posted 26 June 2009
Posted to: Cancer, Developmental Biology, Bioinformatics, Earth & Environment, Evolutionary Biology
Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian
Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung can…
Received 12 June 2009 00:40 UTC; Posted 18 June 2009
Posted to: Cancer, Pharmacology
3D model of amphioxus steroid receptor complexed with estradiol
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chorda…
Received 03 June 2009 21:14 UTC; Posted 05 June 2009
Posted to: Cancer, Developmental Biology, Bioinformatics, Evolutionary Biology
Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model
Using an adenoviral system as a delivery mediator of therapeutic gene, we investigated the therapeutic effects of the use of combined MDR1 shRNA and human NIS (hNIS) radioiodine gene therapy in…
Received 02 June 2009 13:12 UTC; Posted 02 June 2009
Posted to: Cancer
Rethinking Leucine Zipper – a ubiquitous signal transduction motif
In this essay we attempt to reconsider the concept of the “Leucine Zipper” (LZ) protein oligomerization motif. Reasoning on the wealth of existing data, we suggest that despite of the structural si…
Received 22 May 2009 07:26 UTC; Posted 22 May 2009
Posted to: Cancer, Immunology, Molecular Cell Biology, Bioinformatics
