Cancer
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MicroDNAs and Transcriptional Regulation
Synthetic "microDNAs (MIDs)"is a new class of ~ 20-25 nucleotide-long DNAs capable of repressing the activity of the target gene at the level of transcription by mechanisms that have not …
Received 04 November 2009 08:33 UTC; Posted 04 November 2009
Posted to: Cancer, Genetics & Genomics, Molecular Cell Biology
PSA Dynamics traditionally evaluated with an inadequate formula
The PSA doubling time is usually calculated from measured PSA values with an inadequate formula that tacitly assumes the absence of that process, which it is supposed to reveal. We present a modifi…
Received 01 November 2009 23:59 UTC; Posted 03 November 2009
Posted to: Cancer
Suppression of cell cycle progression by Jun dimerization protein (JDP2) involves down-regulation of cyclin A2
We report here a novel role for Jun dimerization protein-2 (JDP2) as a regulator of the progression of normal cells through the cell cycle. To determine the role of JDP2 in vivo, we generated Jdp2 …
Received 08 October 2009 07:50 UTC; Posted 08 October 2009
Posted to: Cancer
Public awareness of cancer in Britain: a population-based survey of adults
Objective: To assess public awareness of cancer warning signs, anticipated delay, and perceived barriers to seeking medical advice in the British population. Methods: We carried out a populat…
Received 30 September 2009 20:17 UTC; Posted 01 October 2009
Posted to: Cancer
A randomised controlled trial of an intervention to promote early presentation of breast cancer in older women: effect on breast cancer awareness
There is virtually no evidence for the effectiveness of interventions to promote early presentation in breast cancer. We tested the efficacy of an intervention to equip older women with the knowled…
Received 30 September 2009 20:10 UTC; Posted 01 October 2009
Posted to: Cancer
Interventions to Promote Cancer Awareness and Early Presentation: Systematic Review
Low cancer awareness contributes to delay in presentation for cancer symptoms and may lead to delay in cancer diagnosis. The aim of this study was to review the evidence for the effectiveness of in…
Received 01 October 2009 14:05 UTC; Posted 02 October 2009
Posted to: Cancer
Nuclear DNA and protein content evaluation in Taxus plant cell cultures using multiparameter flow cytometry
Plant cell cultures of Taxus provide the most reliable production methods for the anti-cancer drug paclitaxel. In order to comprehend the inherent culture heterogeneity and production variability i…
Received 28 September 2009 22:50 UTC; Posted 01 October 2009
Posted to: Biotechnology, Cancer, Developmental Biology, Genetics & Genomics, Plant Biology
Aven and Survivin Expression in Egyptian Acute Leukemia and Their Relation to Apoptosis
Background: Several anti apoptotic signals have been recently identified. Aven and Survivin are broadly expressed and are conserved in mammalian species. Patients and Methods: 39 AML and 25 ALL wer…
Received 16 September 2009 13:19 UTC; Posted 23 September 2009
Posted to: Cancer
Polymorphisms of TSER and MTHFR are associated with prognosis of fluoropyrimidine-based therapy in colorectal cancer patients
This study was designed to investigate the influence of TSER and MTHFR polymorphisms on the clinical outcomes of patients with colorectal cancer receiving 5-FU-based chemotherapy. Genomic DNA was i…
Received 11 September 2009 00:36 UTC; Posted 11 September 2009
Posted to: Cancer, Genetics & Genomics
The Sonic Hedgehog Pathway Stimulates Prostate Tumor Growth by Paracrine Signaling and Recaptures Embryonic Gene Expression in Tumor Myofibroblasts
The Hedgehog (Hh) pathway contributes to prostate cancer growth and progression. The presence of robust Shh expression in both normal prostate and localized cancer challenged us to explain the uniq…
Received 24 August 2009 17:35 UTC; Posted 26 August 2009
Posted to: Cancer, Developmental Biology
