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Polyethylenimine-Modified Multiwalled Carbon Nanotubes for Plasmid DNA Gene Delivery
An efficient molecular delivery technique based on the transporting high-molecular-weight PEI 600K-modified multiwalled carbon nanotubes (PEI 600K-MWCNTs) into cell membranes is reported. The PEI 6…
Received 05 January 2009 07:22 UTC; Posted 07 January 2009
Posted to: Biotechnology, Cancer, Chemistry
The Hepatocellular Hypoxia Criteria:2’Nitroimidazole Effect on Hepatocyte Carbohydrate Metabolizing Enzymes
Aim: to understand the 2’-nitroimidazole induced hypoxia and liver cell interaction, we proposed a “Hapatocellular Hypoxia Criteria”. Hypothesis: The nitroimidazole induced metabolic energy loss a…
Received 30 December 2008 21:07 UTC; Posted 30 December 2008
Posted to: Biotechnology, Cancer, Pharmacology
Expression profile of genes involved in hydrogen sulphide liberation by Saccharomyces cerevisiae grown under different nitrogen concentrations
The present work aims to elucidate molecular mechanisms underlying hydrogen sulphide production in S. cerevisiae associated to nitrogen deficiency. To assess, at a genome-wide level, how the yeas…
Received 30 December 2008 18:44 UTC; Posted 02 January 2009
Posted to: Biotechnology, Microbiology
The Entropic Landscape of proteins revealing protein folding mechanism
It has long since been a mystery why most proteins fold within a flash of time into particular structures out of astronomically large numbers of possible conformations. Even more confusing is that …
Received 25 December 2008 10:15 UTC; Posted 28 December 2008
Posted to: Biotechnology, Molecular Cell Biology, Bioinformatics
Expression of Green Fluorescence Protein (GFP) in Zebrafish Muscle through Injection: A Gene Therapy Model
Expression of the target gene is important for gene therapy. Presently, localized transgenesis is used for gene therapy which can be achieved by a target gene expression. Here, we have reported the…
Received 25 December 2008 07:28 UTC; Posted 28 December 2008
Posted to: Biotechnology, Genetics & Genomics, Pharmacology
Micro-magnetic resonance imaging (micro-MRI) study on the sepsis effected eyeball of zebrafish
We have studied the normal and sepsis effected zebrafish eyeball with micro-magnetic resonance imaging (micro-MRI). T2 weighted image was studied and pixel-wise T2 maps were co registered among the…
Received 21 December 2008 09:16 UTC; Posted 22 December 2008
Posted to: Biotechnology
Three Dimensional Quantitative Structure-Activity Relationships of Sulfonamides Binding Monoclonal Antibody by Comparative Molecular Field Analysis
The three-dimensional quantitative structure-activity relationship (3D-QSAR) model of sulfonamide analogs binding a monoclonal antibody (MabSMR) produced against sulfamerazine, was carried out by c…
Received 12 December 2008 02:36 UTC; Posted 12 December 2008
Posted to: Biotechnology, Chemistry, Pharmacology
21 Tesla Micro-MRI of Rat Skin
Aim: A rapid ultra high resolution ex vivo MRI imaging method was evaluated to visualize rat skin structure. The main objectives were:1.qualitative assessment of viable epidermis, hair, oil and f…
Received 11 December 2008 20:39 UTC; Posted 11 December 2008
Posted to: Biotechnology
Description of a method for localizing swarming mosquitoes and other insects in 3D space with visualizations
Male mosquitoes swarm to find mates, but the characteristics of these swarms have not yet been quantitatively analyzed in the field. This paper describes a simple method used recently to localize i…
Received 03 December 2008 13:20 UTC; Posted 04 December 2008
Posted to: Biotechnology, Ecology
New fungal sources for α-L-Rhamnosidase: an important enzyme used in the synthesis of drugs and drug precursors
Two fungal strains were isolated and tentatively identified as Penicillium VY and Aspergillus VY. All the isolated species show the maximum production on third day in a liquid culture media. The pH…
Received 24 November 2008 10:38 UTC; Posted 24 November 2008
Posted to: Biotechnology, Chemistry, Microbiology
