Biotechnology
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A novel strategy for the targeted analysis of protein and peptide metabolites
The detection and quantitation of exogenously administered biological macromolecules (e.g. vaccines, peptide and protein therapeutics) and their metabolites is frequently complicated by the presenc…
Received 29 September 2009 07:56 UTC; Posted 29 September 2009
Posted to: Biotechnology, Immunology, Pharmacology
Nuclear DNA and protein content evaluation in Taxus plant cell cultures using multiparameter flow cytometry
Plant cell cultures of Taxus provide the most reliable production methods for the anti-cancer drug paclitaxel. In order to comprehend the inherent culture heterogeneity and production variability i…
Received 28 September 2009 22:50 UTC; Posted 01 October 2009
Posted to: Biotechnology, Cancer, Developmental Biology, Genetics & Genomics, Plant Biology
Iron (FeSO4) Bioavailability in Obese Subjects Submitted to Bariatric Surgery
Objective: To determine iron bioavailability in obese subjects after the ingestion of a nutritional supplement containing multiple nutrients. Methods: Fourteen persons were studied before and after…
Received 19 September 2009 19:27 UTC; Posted 21 September 2009
Posted to: Biotechnology, Chemistry, Developmental Biology
Prediction of Evolutionarily important catalytic amino acid of Mycobacterium tuberculosis O-Succinylbenzoate synthase through in silico mutational analysis
The emergence of tuberculosis resistant to multiple, first- and second-line antibiotics poses challenges to a global control strategy that relies on standard drug treatment regimens. The high drug-...
Received 17 September 2009 10:51 UTC; Posted 18 September 2009
Posted to: Biotechnology, Microbiology, Pharmacology, Bioinformatics
Cost effective mass multiplication of Gymnema sylvestre in hydroponic system
Present experiment was designed with an objective to develop a cost efficient mass multiplication method for Gymnema sylvestre using hydroponic system. A plastic tub, with polyethylene cover, conta…
Received 16 September 2009 08:29 UTC; Posted 16 September 2009
Posted to: Biotechnology, Plant Biology
Computational binding mechanism of Mycobacterium tuberculosis UDP-NAG enolpyruvyl transferase (MurA) with inhibitors fosfomycin, cyclic disulfide analog RWJ-3981, pyrazolopyrimidine analog RWJ-110192, purine analog RWJ-140998, 5-sulfonoxy-anthranilic aci
Worldwide, tuberculosis (TB) remains the most frequent and important infectious disease causing morbidity and death. One-third of the world’s population is infected with Mycobacterium tuberculosis …
Received 08 September 2009 05:44 UTC; Posted 08 September 2009
Posted to: Biotechnology, Microbiology, Bioinformatics
Technical Comments on “Greater Transportation Energy and GHG Offsets from BioelectricityThan Ethanol”
Campbell et al. [Report in Science 2009 (May 22), 324, 1055] analyzed two scenarios where bioenergy crops were used for transportation – (1) cellulosic ethanol production by biorefineries for inte…
Received 06 September 2009 15:04 UTC; Posted 07 September 2009
Posted to: Biotechnology, Chemistry, Earth & Environment
Cryopreservation of cell/hydrogel constructs based on a new cell-assembling technique
Organ manufacturing products hold the promise to be used widely in the future for complex organ failings. The cryopreservation of the product is a very important step in the commercialization activ…
Received 05 September 2009 01:10 UTC; Posted 09 September 2009
Posted to: Biotechnology
Systems Biology Graphical Notation: Process Description language Level 1
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society wou…
Received 04 September 2009 22:59 UTC; Posted 07 September 2009
Posted to: Biotechnology, Bioinformatics
Polymerase-endonuclease amplification reaction for large-scale enzymatic production of antisense oligonucleotide
Synthetic oligonucleotides are contaminated with highly homologous failure sequences. Oligonucleotide synthesis is difficult to scale up because it requires expensive equipments, hazardous chemical…
Received 02 September 2009 04:00 UTC; Posted 02 September 2009
Posted to: Biotechnology, Chemistry, Pharmacology