Bioinformatics
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An artificial spiking synapse made of molecules and nanoparticles
Molecule-based devices are envisioned to complement silicon devices by providing new functions or already existing functions at a simpler process level and at a lower cost by virtue of their self-o…
Received 06 April 2009 09:37 UTC; Posted 06 April 2009
Posted to: Neuroscience, Bioinformatics
Evaluation of diversity, specialization, and gene specificity in transcriptomes
The transcriptome is a set of genes transcribed in a given tissue under specific conditions and can be characterized by a list of genes with their corresponding frequencies of transcription. Transc…
Received 31 March 2009 19:17 UTC; Posted 02 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Memristance can explain Spike-Time-Dependent-Plasticity in Neural Synapses
Interdisciplinary research broadens the view of particular problems yielding fresh and possibly unexpected insights. This is the case of neuromorphic engineering where technology and neuroscience c…
Received 31 March 2009 14:32 UTC; Posted 31 March 2009
Posted to: Neuroscience, Bioinformatics
Biased amino acid composition in warm-blooded animals
Among eubacteria and archeabacteria, amino acid composition is correlated with habitat temperatures. In particular, species living at high temperatures have proteins enriched in the amino acids E-R…
Received 24 March 2009 16:39 UTC; Posted 25 March 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Entropic Landscape: the method to predict folding patterns and regional stability of proteins
I propose a new method to calculate the entropy of a given protein sequence fragment. The set of fragment entropies over all possible fragments of the given sequence shows which region of the seque…
Received 24 March 2009 10:19 UTC; Posted 26 March 2009
Posted to: Bioinformatics
Delayed-Type hypersensitivity to latex: Computational prediction of MHC class II epitopes on latex allergens
Delayed type hypersensitivity to natural rubber latex is rare compared to IgE mediated immediate reactions. Binding of allergens to MHC Class II is a crucial step in the presentation of antigens to…
Received 06 March 2009 10:17 UTC; Posted 06 March 2009
Posted to: Immunology, Bioinformatics
Molecular phylogenies and evolutionary behavior of AhR (aryl hydrocarbon receptor) pathway genes in aquatic animals
Phylogenetic analysis of AhR pathway genes and their evolutionary rate variations were studied on aquatic animals. The gene sequences for the proteins involved in this pathway were obtained from ma…
Received 05 March 2009 16:39 UTC; Posted 17 March 2009
Posted to: Bioinformatics, Evolutionary Biology
Phylogeny of conserved adenines in linkers of Group-I introns
We have analyzed the linkers in group-I introns, a characteristic region that is crucial to the folding and splicing process of the folded RNA, in seventy sequences spreading across r-RNA, t-RNA an…
Received 28 February 2009 19:36 UTC; Posted 03 March 2009
Posted to: Molecular Cell Biology, Bioinformatics, Evolutionary Biology
A stable backbone for the fungi
Fungi are abundant in the biosphere. They have fascinated mankind as far as written history goes and have considerably influenced our culture. In biotechnology, cell biology, genetics, and life sci…
Received 24 February 2009 09:27 UTC; Posted 25 February 2009
Posted to: Ecology, Bioinformatics
Large-scale imaging of brain network activity from >10,000 neocortical cells
Large-scale recording from populations of neurons is a promising strategy in the study of complex brain function. Here we introduce a simple optical technique that simultaneously probes the calcium…
Received 23 February 2009 03:59 UTC; Posted 23 February 2009
Posted to: Neuroscience, Bioinformatics