Bioinformatics
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Computational binding mechanism of Mycobacterium tuberculosis UDP-NAG enolpyruvyl transferase (MurA) with inhibitors fosfomycin, cyclic disulfide analog RWJ-3981, pyrazolopyrimidine analog RWJ-110192, purine analog RWJ-140998, 5-sulfonoxy-anthranilic aci
Worldwide, tuberculosis (TB) remains the most frequent and important infectious disease causing morbidity and death. One-third of the world’s population is infected with Mycobacterium tuberculosis …
Received 08 September 2009 05:44 UTC; Posted 08 September 2009
Posted to: Biotechnology, Microbiology, Bioinformatics
Systems Biology Graphical Notation: Activity Flow language Level 1
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society wou…
Received 05 September 2009 03:20 UTC; Posted 07 September 2009
Posted to: Bioinformatics
Systems Biology Graphical Notation: Process Description language Level 1
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society wou…
Received 04 September 2009 22:59 UTC; Posted 07 September 2009
Posted to: Biotechnology, Bioinformatics
Systems Biology Graphical Notation: Entity Relationship language Level 1
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society wou…
Received 04 September 2009 07:09 UTC; Posted 04 September 2009
Posted to: Bioinformatics
MUEGANO: A divide and conquer algorithm to overcome memory limitations when assembling shotgun projects
When assembling a large quantity of reads in a genomic shotgun project a serious limitation is the amount of random access memory (RAM) of the computers used in the project. This arises because all…
Received 02 September 2009 14:58 UTC; Posted 02 September 2009
Posted to: Genetics & Genomics, Bioinformatics
Evaluation of protein surface roughness index using its heat denatured aggregates
Recent research works on potential of different protein surface describing parameters to predict protein surface properties gained significance for its possible implication in extracting clues on p…
Received 27 August 2009 09:16 UTC; Posted 27 August 2009
Posted to: Biotechnology, Bioinformatics
Innovation in cardiology. A new diagnostic standard establishing criteria of quantitative & qualitative evaluation of main parameters of the cardiac & cardiovascular system according to ECG and Rheo based on cardiac cycle phase analysis
Over more than 50 years the theory of functioning of the cardiac & cardiovascular system remained unchanged. As a rule, all conventional diagnostics methods are based on statistics data on changes …
Received 02 September 2009 04:53 UTC; Posted 02 September 2009
Posted to: Bioinformatics
A Study of the Mechanism of Action of Zervamicin IIB Peptide Antibiotic by Molecular Dynamics Simulation
We model mechanism of action of a channel-forming peptide antibiotic, zervamicin IIB, by molecular dynamics (MD) simulation. Interaction of this peptide with neutral and negatively charged lipid bi…
Received 16 August 2009 20:29 UTC; Posted 17 August 2009
Posted to: Pharmacology, Bioinformatics
Data Mining for Simple Sequence Repeats in Oil Palm Expressed Sequence Tags
Expressed Sequence Tags or ESTs are small pieces of DNA sequence that are generated by sequencing either one or both ends of an expressed gene. ESTs provide researchers with a quick and inexpensive…
Received 08 August 2009 12:55 UTC; Posted 10 August 2009
Posted to: Genetics & Genomics, Bioinformatics
Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16α-hydroxylation by Cytochrome P450-2C11. Docking stu…
Received 03 August 2009 05:39 UTC; Posted 03 August 2009
Posted to: Chemistry, Bioinformatics
