Bioinformatics
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Interspecific differences in single nucleotide polymorphisms (SNPs) and indels in expressed sequence tag libraries of oil palm Elaeis guineensis and E. oleifera
Oil palm is the second largest source of edible oil, which meets one-fifth of global demands of oils and fats. Expressed sequence tag (EST) sequencing programs have provided a wealth of information…
Received 24 September 2009 05:38 UTC; Posted 24 September 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Primate phylogeny: molecular evidence for a pongid clade excluding humans and a prosimian clade containing tarsiers
Interpretations of molecular data by the modern evolution theory are often sharply inconsistent with paleontological results. This is to be expected since the theory is only true for microevolutio…
Received 21 September 2009 22:18 UTC; Posted 22 September 2009
Posted to: Bioinformatics, Evolutionary Biology
Prediction of Evolutionarily important catalytic amino acid of Mycobacterium tuberculosis O-Succinylbenzoate synthase through in silico mutational analysis
The emergence of tuberculosis resistant to multiple, first- and second-line antibiotics poses challenges to a global control strategy that relies on standard drug treatment regimens. The high drug-...
Received 17 September 2009 10:51 UTC; Posted 18 September 2009
Posted to: Biotechnology, Microbiology, Pharmacology, Bioinformatics
Extracting conclusion sections from PubMed abstracts for rapid key assertion integration in biomedical research
Key assertions are extracted from “conclusions” sections of PubMed abstracts andconverted into Semantic Web / Linked Data format. The results are made accessible viafiles, a SPARQL endpoint, an…
Received 17 September 2009 10:35 UTC; Posted 21 September 2009
Posted to: Bioinformatics
Pandemic (H1N1) 2009 Cluster Analysis: A Preliminary Assessment
Pandemic (H1N1) 2009 virus has been causing major concerns around the world because of its epidemic potential, rapid dissemination, rate of mutations, and the number of fatalities. One way to gain …
Received 16 September 2009 20:24 UTC; Posted 16 September 2009
Posted to: Genetics & Genomics, Microbiology, Bioinformatics
Novel determinants describe chaperonin substrate proteins
Molecular chaperones ensure that their substrate proteins reach the functional native state and prevent their aggregation. The bacterial GroEL/ES chaperonin system is understood in great detail on …
Received 15 September 2009 12:00 UTC; Posted 15 September 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Ontology-based Trial Management System (ObTiMA)
The ACGT project which aims to foster the sharing of research result from both, clinical and molecular research for the benefit of cancer patients uses ontology-driven semantic services. One novelt…
Received 12 September 2009 15:23 UTC; Posted 14 September 2009
Posted to: Bioinformatics
Frequency-dependent selection predicts patterns of radiations and biodiversity
Most empirical studies support a decline in speciation rates through time, although evidence for constant speciation rates also exists. Declining rates have been explained by invoking niche-filling…
Received 12 September 2009 05:41 UTC; Posted 14 September 2009
Posted to: Ecology, Genetics & Genomics, Bioinformatics, Earth & Environment, Evolutionary Biology
In silico microRNA identification from paprika (Capsicum annuum) ESTs
A total of 33,311 Expressed Sequence Tags (EST) of paprika were mined from the GenBank EST database. The redundancy of the EST sequences was removed using CAP3 and it resulted 4,541 contigs 8,539 s…
Received 24 September 2009 05:19 UTC; Posted 24 September 2009
Posted to: Genetics & Genomics, Bioinformatics, Plant Biology
Modeling, Simulation and Application of Bacterial Transduction in Genetic Algorithms
At present, all methods in Evolutionary Computation are bioinspired in the fundamental principles of neo-Darwinism as well as on a vertical gene transfer. Thus, on a mechanism in which an organism …
Received 08 September 2009 09:11 UTC; Posted 08 September 2009
Posted to: Microbiology, Bioinformatics, Evolutionary Biology