Bioinformatics
Sign up for alerts
Bacterial Capnine Blocks Transcription of Human Antimicrobial Peptides
The US CDC believes that 65% of all infections in developed countries may be caused by pathogens in biofilms. Electron Microscopy has shown that these bacterial communities can evade phagocytosis, ...
Received 21 June 2007 16:29 UTC; Posted 22 June 2007
Posted to: Immunology, Microbiology, Bioinformatics
Revolutionizing scientific communication and collaboration
This presentation introduces new web-based ways of scientific communication and collaboration. It focuses on wikis and the First Online EMBL PhD Symposium as an example of an online conference.
Received 21 June 2007 10:15 UTC; Posted 21 June 2007
Posted to: Bioinformatics
Folding pathway of the B1 domain of protein G explored by a multiscale modeling
The understanding of the folding mechanisms of single domain proteins is an essential step in the understanding of protein folding in general. Recently, we developed a mesoscopic CABS protein model…
Received 20 June 2007 13:55 UTC; Posted 20 June 2007
Posted to: Molecular Cell Biology, Bioinformatics
The CombiUgi Project and Closing the Open Science Loop
This presentation combines 2 blog posts explaining the CombiUgi project and the predicted anti-tumor activity of a virtual library of 68,000 compounds.
Received 19 June 2007 16:23 UTC; Posted 20 June 2007
Posted to: Cancer, Chemistry, Bioinformatics
Promoter regions of many neural- and nutrition-related genes have experienced positive selection during human evolution
Surveys of protein-coding sequences for evidence of positive selection in humans and chimpanzees have flagged surprisingly few genes known to be involved in neural or nutritional processes, despite…
Received 18 June 2007 21:04 UTC; Posted 13 July 2007
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Molecular Static and Dynamic Analyses reveal Flaw in Murine Model used by US FDA to Detect Drug Carcinogenicity
The US FDA currently accepts carcinogenicity studies of pharmaceutical drugs based on murine models. In addition to 6 month studies with p53(+/-) and ras.H2 transgenic mice, lifetime studies (typic…
Received 15 June 2007 18:05 UTC; Posted 15 June 2007
Posted to: Biotechnology, Cancer, Immunology, Pharmacology, Bioinformatics
Fast and Scriptable Molecular Graphics in Web Browsers without Java3D
Jmol is a free, open source molecule viewer for chemistry and biochemistry. It is cross-platform, running on Windows, Mac OS X, and Linux/Unix systems. The software consists of three parts: the Jmo…
Received 14 June 2007 14:09 UTC; Posted 14 June 2007
Posted to: Chemistry, Bioinformatics
Genes2Networks: Connecting Lists of Proteins by Using Background Literature-based Mammalian Networks
In recent years, in-silico literature-based mammalian protein-protein interaction network datasets have been developed. These datasets contain binary interactions extracted manually from legacy exp…
Received 07 June 2007 15:27 UTC; Posted 08 June 2007
Posted to: Biotechnology, Molecular Cell Biology, Bioinformatics
Specificity and Evolvability in Eukaryotic Protein Interaction Networks
Progress in uncovering the protein interaction networks of several species has led to questions of what underlying principles might govern their organization. Few studies have tried to determine th…
Received 28 February 2007 20:11 UTC; Posted 02 March 2007
Posted to: Bioinformatics, Evolutionary Biology
Intracellular Regulatory Networks are close to Monotone Systems
Several meso-scale biological intracellular regulatory networks that have specified directionality of interactions have been recently assembled from experimental literature. Directed networks where…
Received 23 January 2007 16:57 UTC; Posted 23 January 2007
Posted to: Molecular Cell Biology, Bioinformatics
