Bioinformatics
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The Role of Neuregulin 1 in Schizophrenia: A Bioinformatics Approach
Context: Notwithstanding the great number of studies on the etiology and pathophysiology of schizophrenia, both issues remain far from being fully understood. Schizophrenia seems to be related to…
Received 27 October 2009 21:54 UTC; Posted 28 October 2009
Posted to: Genetics & Genomics, Neuroscience, Bioinformatics
BRAGOMAP – a new Perl script for high throughoutput blast results analysis including GO and MapMan automatic annotations
Analyzing of sequences similarities is the first and most important method used to find out the function of unknown nucleotides. Searching of homologs should be done carefully not to loose any impo…
Received 25 October 2009 19:49 UTC; Posted 26 October 2009
Posted to: Genetics & Genomics, Bioinformatics, Plant Biology
16S rRNA based identification of Aeromonas sp. kumar by constructing phylogenetic tree and identification of regulatory elements from the harmful Red Tide bloom, Gulf of Mannar
A bacterial strain, designated Aeromonas sp. kumar, was isolated from a water sample collected from Red tide Bloom occurred in the region of Gulf of Mannar region, Puthumadam Coast, India and the…
Received 28 October 2009 02:02 UTC; Posted 28 October 2009
Posted to: Ecology, Microbiology, Bioinformatics
Chromosomal mutational algebra: a new algebra to manipulate chromosomal mutation
This study leads to a new algebra. An algebra is defined on the common mechanisms of chromosomal mutation. The algebra (SΨ(C), *, ’, Δ, D) is constructed for a given C and Ψ...
Received 20 October 2009 03:43 UTC; Posted 20 October 2009
Posted to: Genetics & Genomics, Bioinformatics
Towards a genome-wide transcriptogram: the Saccharomyces cerevisiae case
A genome modular classification that associates cellular processes to modules could lead to a method to quantify the differences in gene expression levels in different cellular stages or conditions…
Received 16 October 2009 15:38 UTC; Posted 19 October 2009
Posted to: Biotechnology, Genetics & Genomics, Bioinformatics
Ten Simple Rules for Searching and Organizing the Scientific Literature
The exponentially increasing number of published papers (1.4 million per year by one estimate) makes it more and more difficult for us to manage the flood of scientific information. Each of us has …
Received 16 October 2009 05:03 UTC; Posted 16 October 2009
Posted to: Bioinformatics
Genome-scale approach proves that the lungfish-coelacanth sister group is the closest living relative of tetrapods with the BEST program
The origin of tetrapods has not been resolved for decades. Three principal hypotheses (lungfish-tetrapod, coelacanth-tetrapod, or lungfish-coelacanth sister group) have been proposed. We used the B…
Received 15 October 2009 04:03 UTC; Posted 15 October 2009
Posted to: Ecology, Genetics & Genomics, Bioinformatics, Evolutionary Biology
A new multicompartmental reaction-diffusion modeling method links transient membrane attachment of E. coli MinE to E-ring formation
Many important cellular processes are regulated by reaction-diffusion (RD) of molecules that takes place both in the cytoplasm and on the membrane. To model and analyze such multicompartmental proc…
Received 09 October 2009 08:58 UTC; Posted 09 October 2009
Posted to: Developmental Biology, Microbiology, Bioinformatics
Mega- change gene copies are produced by reverse transcription of precursor RNA with replaced introns.
This report describes the presence of copy genes in plants where the sequence similarity to their parental genes is almost completely limited to limited to the exons. Evidence is presented that ind…
Received 07 October 2009 15:02 UTC; Posted 07 October 2009
Posted to: Genetics & Genomics, Bioinformatics, Plant Biology, Evolutionary Biology
Simple SVM based whole-genome segmentation
We present a support vector machine (SVM) based framework for DNA segmentation into binary classes. Two applications are explored: transcription start site prediction and transcription factor bindi…
Received 29 September 2009 07:20 UTC; Posted 29 September 2009
Posted to: Bioinformatics