Bioinformatics
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Transformation of metabolism with age and lifestyle in Antarctic seals: a case study of systems biology approach to cross-species microarray experiment
Background: The metabolic transformation that changes Weddell seal pups born on land into aquatic animals is not only interesting for the study of general biology, but it also provides a model …
Received 28 June 2009 22:50 GMT; Posted 29 June 2009
Posted to: Developmental Biology, Ecology, Bioinformatics
Independent elaboration of steroid hormone signaling pathways in Metazoans
Steroid hormones regulate many physiological processes in vertebrates, nematodes and arthropods through binding to nuclear receptors (NR), a metazoan-specific family of ligand-activated transcripti…
Received 25 June 2009 20:26 GMT; Posted 26 June 2009
Posted to: Cancer, Developmental Biology, Bioinformatics, Earth & Environment, Evolutionary Biology
An evaluation of taxonomic name finding & next steps in Biodiversity Heritage Library (BHL) developments
The Biodiversity Heritage Library (BHL) is an international consortium of natural history libraries that are actively scanning scientific literature from their collections and publishing the digiti…
Received 25 June 2009 18:08 GMT; Posted 26 June 2009
Posted to: Bioinformatics, Earth & Environment
Range-based techniques for discovering optimality and analyzing scaling relationships in neuromechanical systems
In this paper, a method for decoupling the neuromuscular function of a set of limbs from the role morphology plays in regulating the performance of an activity is introduced. This method is based o…
Received 16 June 2009 15:54 GMT; Posted 18 June 2009
Posted to: Neuroscience, Bioinformatics
How do we quantify biodiversity? All the evidence in one place.
Biodiversity is a multi-dimensional concept that is represented by a large variety of measures. This complexity and lack of consistency limits the development of a coherent scientific understanding…
Received 05 June 2009 11:06 GMT; Posted 08 June 2009
Posted to: Ecology, Bioinformatics
3D model of amphioxus steroid receptor complexed with estradiol
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chorda…
Received 03 June 2009 21:05 GMT; Posted 05 June 2009
Posted to: Cancer, Developmental Biology, Bioinformatics, Evolutionary Biology
Reconstruction of an in silico metabolic model of Arabidopsis thaliana through database integration
The number of genome-scale metabolic models has been rising quickly in recent years, and the scope of their utilization encompasses a broad range of applications from metabolic engineering to biolo…
Received 02 June 2009 17:06 GMT; Posted 03 June 2009
Posted to: Bioinformatics
Structural Analysis of Polarizing Indels Argues the Root of the Tree of Life is Near the Chloroflexi
Determining which branches of the tree of life have derived features narrows down the possible location of the root. Currently the polarization of indels done by Lake et al.1-5 and the polarizi…
Received 26 May 2009 17:55 GMT; Posted 27 May 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Annotation of SBML Models Through Rule-Based Semantic Integration
Motivation: The creation of accurate quantitative Systems Biology Markup Language (SBML) models is a time-intensive, manual process often complicated by the many data sources and formats required…
Received 26 May 2009 13:12 GMT; Posted 29 May 2009
Posted to: Bioinformatics
Networking Phylogeny for Indo-European and Austronesian Languages
Harnessing cognitive abilities of many individuals, a language evolves upon their mutual interactions establishing a persistent social environment to which language is closely attuned. Human histor…
Received 25 May 2009 11:09 GMT; Posted 27 May 2009
Posted to: Bioinformatics
