Bioinformatics
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LBFO: toward an artificial language for ontology development
The syntax of LBFO represents the initial step toward the creation of a rigorously characterized, recursively defined, artificial language for the sole purpose of ontology development. The underlyi…
Received 23 November 2009 13:55 UTC; Posted 23 November 2009
Posted to: Bioinformatics
The INCF Digital Atlasing Program: Report on Digital Atlasing Standards in the Rodent Brain
The goal of the INCF Digital Atlasing Program is to provide the vision and direction necessary to make the rapidly growing collection of multidimensional data of the rodent brain (images, gene expr…
Received 23 November 2009 11:57 UTC; Posted 24 November 2009
Posted to: Neuroscience, Bioinformatics
Evaluation of the Cell Ontology (CL)
An ontological representation of the entities relevant to biological research is urgently needed. The cell ontology developed by Bard and colleagues (CL) (Bard et al. 2005) makes a significant con…
Received 12 November 2009 11:30 UTC; Posted 12 November 2009
Posted to: Bioinformatics
Malaria Diagnosis and the Plasmodium Life Cycle: the BFO Perspective
Definitive diagnosis of malaria requires the demonstration through laboratory tests of the presence within the patient of malaria parasites or their components. Since malaria parasites can be prese…
Received 07 November 2009 15:11 UTC; Posted 09 November 2009
Posted to: Bioinformatics
The NCBO OBOF to OWL Mapping
Two of the most significant formats for biomedical ontologies are the Open Biomedical Ontologies Format (OBOF) and the Web Ontology Language (OWL). To make it possible to translate ontologies betwe…
Received 03 November 2009 20:16 UTC; Posted 04 November 2009
Posted to: Bioinformatics
Organising metabolic networks: cycles in flux distributions
Metabolic networks are among the most widely studied biological systems. The topology and interconnections of metabolic reactions have been well described for many species, but are not sufficient t…
Received 02 November 2009 16:01 UTC; Posted 02 November 2009
Posted to: Bioinformatics
Accurate telemonitoring of Parkinson’s disease progression by non-invasive speech tests
Tracking Parkinson’s disease (PD) symptom progression often uses the Unified Parkinson’s Disease Rating Scale (UPDRS), which requires the patient’s presence in clinic, and time-consuming physical e…
Received 29 October 2009 12:52 UTC; Posted 29 October 2009
Posted to: Neuroscience, Bioinformatics
Voluntary universal testing and treatment is unlikely to lead to HIV elimination: a modeling analysis
Recently Granich et al. at the World Health Organization (WHO) concluded, using mathematical modeling, that HIV epidemics could be eliminated within a decade. They assumed all individuals would be …
Received 29 October 2009 08:46 UTC; Posted 29 October 2009
Posted to: Bioinformatics
Design of a dynamic model of genes with multiple autonomous regulatory modules by evolution in silico
A new approach to design a dynamic model of genes with multiple autonomous regulatory modules by evolution in silico is proposed. The approach is based on Genetic Algorithms, with new crossover ope…
Received 29 October 2009 00:50 UTC; Posted 29 October 2009
Posted to: Biotechnology, Developmental Biology, Genetics & Genomics, Bioinformatics, Evolutionary Biology
SSR – Identification from EST
Tutorial of Identification of SSR from EST resources using online Tools
Received 28 October 2009 10:27 UTC; Posted 28 October 2009
Posted to: Biotechnology, Bioinformatics