Latest Presentations
Using Ontology Fingerprints to Evaluate Genome-wide Association Results
We describe an approach to characterize genes or phenotypes via ontology fingerprints which are composed of Gene Ontology (GO) terms overrepresented among those PubMed abstracts linked to the genes…
Received 29 July 2009 15:37 UTC; Posted 29 July 2009
Posted to: Genetics & Genomics, Bioinformatics
An Advanced Clinical Ontology
This article discusses a fundamental issues of medical ontology based on ontological theory. We focus on “anatomical structure of organs” and “abnormal states in the human body”. On the basis of th…
Received 29 July 2009 08:19 UTC; Posted 29 July 2009
Posted to: Bioinformatics
Dynamic is-a Hierarchy Generation from a Clinical Medical Ontology
This article discusses an ontology-handling technology to provide on-demand reorganization of is-a hierarchy of diseases instead of one fixed hierarchy to cope with various viewpoints which physici…
Received 29 July 2009 07:27 UTC; Posted 29 July 2009
Posted to: Bioinformatics
Concurrent, Collaborative Ontology Building with Collaborative Protégé (CP)
Creation of an ontology according to some common plan is best accomplished collaboratively. This is sometimes contradicted by the distribution of the ontology’s developers. An obvious solution ther…
Received 29 July 2009 16:29 UTC; Posted 29 July 2009
Posted to: Bioinformatics
An Ontology-Based Framework for Clinical Research Databases
The Ontology-Based eXtensible data model (OBX) was developed to serve as a framework for the development of a clinical research database in the Immunology Database and Analysis Portal (ImmPort) sys…
Received 27 July 2009 22:48 UTC; Posted 28 July 2009
Posted to: Bioinformatics
A Quality Evaluation Framework for Bio-Ontologies
Over the past few years the number of bio-ontologies has rapidly increased. The evaluation of ontologies has long been a problematic issue. The growing number of ontologies makes the need for a st…
Received 27 July 2009 20:22 UTC; Posted 27 July 2009
Posted to: Bioinformatics
Metarel: An Ontology to Support the Inferencing of Semantic Web Relations within Biomedical Ontologies
Metarel allows the creation of millions of relational inferences in the RDF Knowledge Base BioGateway, by using five types of SPARUL closure queries. Metarel can be found at “http://www.metarel.org…
Received 25 July 2009 18:55 UTC; Posted 27 July 2009
Posted to: Bioinformatics
Towards an Ontological Representation of Resistance: The Case of MRSa
This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. Resistance terms from various existing ontologies are exami…
Received 27 July 2009 19:12 UTC; Posted 27 July 2009
Posted to: Bioinformatics
LexOWL: A Bridge from LexGrid to OWL
The Lexical Grid project is an on-going community driven initiative that provides a common terminology model to represent multiple vocabulary and ontology sources as well as a scalable and robust A…
Received 27 July 2009 14:25 UTC; Posted 27 July 2009
Posted to: Bioinformatics
Debugging Mappings between Biomedical Ontologies: Preliminary Results from the NCBO BioPortal Mapping Repository
The ability to provide semantic mappings between multiple large biomedical ontologies is considered as a very important, albeit labor-intensive and error-prone task. To facilitate such a process, s…
Received 24 July 2009 00:57 UTC; Posted 24 July 2009
Posted to: Bioinformatics
