Latest Manuscripts
Theoretical studies on the pKa values of perfluoroalkyl carboxylic acids: Non-helical conformation acidity constants for n-perfluorooctanoic acid (n-PFOA)
A molecular mechanics force field method (MMFF94) systematic rotor conformational search was conducted on the well known environmental contaminant n-perfluorooctanoic acid (n-PFOA). The MMFF94 con…
Received 08 October 2009 03:17 UTC; Posted 08 October 2009
Posted to: Chemistry, Earth & Environment
Mega- change gene copies are produced by reverse transcription of precursor RNA with replaced introns.
This report describes the presence of copy genes in plants where the sequence similarity to their parental genes is almost completely limited to limited to the exons. Evidence is presented that ind…
Received 07 October 2009 15:02 UTC; Posted 07 October 2009
Posted to: Genetics & Genomics, Bioinformatics, Plant Biology, Evolutionary Biology
The demonstration of the invariant lipid-free composition and the mechanism varying energy and the main components of some mammal meats consisting of muscle and adipose tissue
Background: The assumption of an invariant fat-free or lipid-free composition is prerequisite for most methods of the estimation of body composition in mammals including human but has not been theo…
Received 07 October 2009 07:43 UTC; Posted 07 October 2009
Posted to: Developmental Biology
Limusaurus and bird digit identity
Limusaurus is a remarkable herbivorous ceratosaur unique among theropods in having digits II, III and IV, with only a small metacarpal vestige of digit I. This raises interesting questions regard…
Received 06 October 2009 03:05 UTC; Posted 06 October 2009
Posted to: Developmental Biology, Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology
Theoretical studies on the pKa values of perfluoroalkyl carboxylic acids: Chain helicity
Semiempirical, ab initio, and density functional theory (DFT) studies were conducted on a homologous series of straight chain perfluoroalkyl carboxylic acids (PFCAs) ranging in chain length from C~...
Received 06 October 2009 04:37 UTC; Posted 06 October 2009
Posted to: Chemistry, Earth & Environment
Variation in PNPLA3 is associated with outcomes in alcoholic liver disease
Two recent genome-wide association studies have described associations of SNP variants in PNPLA3 with nonalcoholic fatty liver and plasma liver enzyme levels in population based cohorts. We inves…
Received 05 October 2009 19:14 UTC; Posted 06 October 2009
Posted to: Genetics & Genomics
New methods for analyzing serological data with applications to influenza surveillance
Two important challenges to the use of serological assays for influenza surveillance include the substantial amount of experimental effort involved, and the inherent noisiness of serological data. ...
Received 05 October 2009 08:10 UTC; Posted 05 October 2009
Posted to: Immunology, Evolutionary Biology
Electron microscopy analysis of FcRγ localization after its capture by T cells by trogocytosis
T cells acquire various proteins from their cellular partners by the process of trogocytosis. We recently demonstrated that the FcγRIIIA receptor and its associated FcRγ are captured by T cells dur…
Received 02 October 2009 14:08 UTC; Posted 05 October 2009
Posted to: Immunology
Interventions to Promote Cancer Awareness and Early Presentation: Systematic Review
Low cancer awareness contributes to delay in presentation for cancer symptoms and may lead to delay in cancer diagnosis. The aim of this study was to review the evidence for the effectiveness of in…
Received 01 October 2009 14:05 UTC; Posted 02 October 2009
Posted to: Cancer
A randomised controlled trial of an intervention to promote early presentation of breast cancer in older women: effect on breast cancer awareness
There is virtually no evidence for the effectiveness of interventions to promote early presentation in breast cancer. We tested the efficacy of an intervention to equip older women with the knowled…
Received 30 September 2009 20:10 UTC; Posted 01 October 2009
Posted to: Cancer
