Latest Manuscripts
On biological homochirality
Generalizing Landau’s spontaneous symmetry breaking arguments using the standard groupoid approach to stereochemistry allows reconsideration of the origin of biological homochirality. On Earth, lim…
Received 26 October 2009 13:56 UTC; Posted 26 October 2009
Posted to: Chemistry, Earth & Environment, Evolutionary Biology
Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD).
Although there is evidence for the involvement of genes of serotonergic and dopaminergic systems in the manifestation of the Behavioural and Psychological Symptoms in Dementia (BPSD), genetic assoc…
Received 23 October 2009 20:37 UTC; Posted 26 October 2009
Posted to: Genetics & Genomics, Neuroscience
Earth History and the Evolution of Caribbean Bats
Although the natural history of the Caribbean is better understood now than ever before, a general biogeographic explanation for the peculiar faunal composition of the islands remains elusive. New …
Received 25 October 2009 21:28 UTC; Posted 26 October 2009
Posted to: Earth & Environment, Evolutionary Biology
Consciousness as Recursive, Spatiotemporal Self-Location
At the phenomenal level, consciousness can be described as a singular, unified field of recursive self-awareness, consistently coherent in a particular way; that of a subject located both spatially…
Received 20 October 2009 18:17 UTC; Posted 23 October 2009
Posted to: Neuroscience
Regulated peristalsis into the acidic region of the Drosophila larval midgut is controlled by a novel component of the Autonomic Nervous System
The underlying cellular and molecular mechanisms that regulate and coordinate critical physiological processes such as peristalsis are complex, often cryptic, and involve the integration of multipl…
Received 19 October 2009 18:20 UTC; Posted 23 October 2009
Posted to: Developmental Biology, Neuroscience
The Origin and Evolution of Viruses as Molecular Organisms
Viruses are the most abundant life forms and the repertoire of viral genes is greater than that of cellular genes. It is also evident that viruses have played a major role in driving cellular evolu…
Received 21 October 2009 18:19 UTC; Posted 23 October 2009
Posted to: Genetics & Genomics, Microbiology, Evolutionary Biology
Endogenous Viral Etiology of Prion Diseases
Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a group of incurable neurodegenerative disorders, including Kuru and Creutzfeldt-Jakob disease in humans, “mad cow” disease …
Received 21 October 2009 18:35 UTC; Posted 23 October 2009
Posted to: Microbiology, Neuroscience, Evolutionary Biology
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains
The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology an…
Received 21 October 2009 18:50 UTC; Posted 23 October 2009
Posted to: Genetics & Genomics, Immunology, Microbiology, Evolutionary Biology
In vitro synergistic anti-prion effect of cholesterol ester modulators
Background. Our studies on the role of cholesterol in prion infection/replication showed that brains and peripheral cells of sheep susceptible to or suffering from Scrapie were characterized by an …
Received 21 October 2009 13:06 UTC; Posted 21 October 2009
Posted to: Microbiology, Neuroscience, Pharmacology
Performance of the ALOGPS 2.1 program for octanol-water partition coefficient prediction with organic chemicals on the Canadian Domestic Substances List
The KOWWIN and ALOGPS octanol-water partition coefficient (Kow) estimation software programs were compared for their capacity to accurately predict log Kow values of 1596 organic compounds on t…
Received 21 October 2009 04:30 UTC; Posted 21 October 2009
Posted to: Chemistry, Pharmacology, Earth & Environment
