Latest Manuscripts
Magnetoencephalography May Allow the Electromagnetic 'Biopsy' of Central Nervous System Neoplastic Tissue
Developing a non-invasive method for definitively diagnosing intracranial neoplasms would reduce the risks involved with diagnosis and improve the treatment of such tumors. We used magnetoencephalo…
Received 13 November 2009 00:00 UTC; Posted 13 November 2009
Posted to: Neuroscience
Evaluation of the Cell Ontology (CL)
An ontological representation of the entities relevant to biological research is urgently needed. The cell ontology developed by Bard and colleagues (CL) (Bard et al. 2005) makes a significant con…
Received 12 November 2009 11:30 UTC; Posted 12 November 2009
Posted to: Bioinformatics
The cultural epigenetics of psychopathology: The missing heritability of complex diseases found?
We extend a cognitive paradigm for gene expression to the epigenetic epidemiology of mental disorders, recognizing the fundamental role that culture plays in human biology as another heritage mecha…
Received 11 November 2009 17:52 UTC; Posted 11 November 2009
Posted to: Developmental Biology, Genetics & Genomics, Neuroscience
In Vitro Bactericidal Activities of Extracts From Ripe and Unripe Fruit of ‘Noni’
In an era of nutraceuticular research, ‘Noni’ fruit is considered as a panacea because of the profound claim on its medicinal uses in treating many diseases inclusive of infections of microbial ori…
Received 06 November 2009 05:30 UTC; Posted 09 November 2009
Posted to: Microbiology, Molecular Cell Biology
Malaria Diagnosis and the Plasmodium Life Cycle: the BFO Perspective
Definitive diagnosis of malaria requires the demonstration through laboratory tests of the presence within the patient of malaria parasites or their components. Since malaria parasites can be prese…
Received 07 November 2009 15:11 UTC; Posted 09 November 2009
Posted to: Bioinformatics
Drone congregation areas of red dwarf honeybee, Apis florea
The drones of dwarf honeybees assemble at the drone congregation areas close to small trees with dense leafage at the heights between 2 to 4 meters.
Received 06 November 2009 14:12 UTC; Posted 06 November 2009
Posted to: Evolutionary Biology
High energy-charged cell factory for heterologous protein synthesis
Overexpression of gluconeogenic phosphoenolpyruvate carboxykinase (PCK) under glycolytic conditions enables Escherichia coli to maintain a greater intracellular ATP concentration and, consequently,...
Received 06 November 2009 01:43 UTC; Posted 06 November 2009
Posted to: Biotechnology
Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women?
Objective: The aim of this study was to determine whether genetic variation at the cannabinoid receptor-1 (CNR1) locus could have an effect on adiposity, fat distribution and obesity-related metabo…
Received 05 November 2009 01:29 UTC; Posted 06 November 2009
Posted to: Genetics & Genomics
9aaTADs mimic DNA to interact with a pseudo-DNA Binding Domain KIX of Med15 (Molecular Chameleons)
The KIX-domain of Gal11/MED15 was shown to interact with short transactivation domain of Pdr1 and Oaf1 (12 and 9 amino acids respectively) annotated to 9aaTAD family. Reported NMR data revealed a s…
Received 03 November 2009 21:11 UTC; Posted 05 November 2009
Posted to: Genetics & Genomics
Common Transactivation Motif 9aaTAD recruits multiple general co-activators TAF9, MED15, CBP and p300
More than 2000 transcription factors are involved in the human gene regulation to provide cellular function and development. Transactivation domain, TAD, mediates the interaction of transcription f…
Received 03 November 2009 12:30 UTC; Posted 05 November 2009
Posted to: Genetics & Genomics
