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Decrease of vanillin sucrose intake by victorious and defeated mice: development of anhedonia?

Natalia N. Kudryavtseva¹, Natalia P. Bondar¹, Irina L. Kovalenko¹ & Damira F. Avgustinovich¹

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1. Institute of Cytology and Genetics SD RAS

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Date:

Received 13 September 2007 06:02 UTC; Posted 13 September 2007

Subjects:

Neuroscience

Tags:

• social interactions
• behavior
• motivation

Abstract:

Hedonic reactions to various rewards play a key role in various forms of motivated behavior. The influence of repeated experience of social victories or defeats in daily agonistic interactions between male mice on voluntary consumption of vanillin sucrose solution used as hedonic reinforcer was studied. Intake of vanillin sucrose solution was shown to decrease in the winners and losers exposed to social confrontations as compared with the controls. Three days of deprivation failed to restore the intake of vanillin sucrose solution to the control level in the losers and did so in the winners. The results obtained imply that similar reaction of animals to a hedonic non-drug reinforcer may have different motivational origin depending on positive or negative social experience.

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This document is licensed to the public under the Creative Commons Attribution 2.5 License

How to cite this document:

Kudryavtseva, Natalia N., Bondar, Natalia P., Kovalenko, Irina L., and Avgustinovich, Damira F.. Decrease of vanillin sucrose intake by victorious and defeated mice: development of anhedonia?. Available from Nature Precedings <http://hdl.handle.net/10101/npre.2007.988.1> (2007)

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