Application of a periodic table for the genetic code of the influenza A/H3N2 virus
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- Institute for Science Education, Physical science
- Document Type:
- Manuscript
- Date:
- Received 09 September 2009 15:17 UTC; Posted 09 September 2009
- Subjects:
- Microbiology
- Abstract:
The progress of life sciences would be greatly enhanced if biological data were available in a manner similar to the periodic table of the elements. Currently, the mutation rules for influenza viruses remain ambiguous. In light of the threat of Avian Influenza there is an urgent need to understand the governing principles behind influenza virus mutations. Here, the applicability of a periodic table for the genetic code of influenza A/H3N2 virus is explored. In addition, two rules regarding single point mutations of the hemagglutinin gene are presented. The first rule states that non-synonymous single point mutations are intimately associated with the first or second base replacements between two congener codons of four groups (5, 6, 9, and 10) in the proposed periodic table. The second rule involves the use of a new index (inversion number) that describes a mutation. This paper will take the first step toward developing an approach for indexing different types of mutations in the influenza genome.
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- License:
- This document is licensed to the public under the Creative Commons Attribution 3.0 License
- How to cite this document:
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Morimoto, Susumu. Application of a periodic table for the genetic code of the influenza A/H3N2 virus. Available from Nature Precedings <http://hdl.handle.net/10101/npre.2009.428.2> (2009)
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Other versions of this document in Nature Precedings
Version number Document title Date v1 Posted 13 August 2007 Other versions of this document elsewhere on the web
None known.
