The most recent version of this document (v2) was posted on 2010 January 06.
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Malaria Diagnosis and the Plasmodium Life Cycle: the BFO Perspective
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- NYS Center of Excellence in Bioinformatics & Life Sciences
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- Document Type:
- Manuscript
- Date:
- Received 07 November 2009 15:11 UTC; Posted 09 November 2009
- Subjects:
- Bioinformatics
- Abstract:
Definitive diagnosis of malaria requires the demonstration through laboratory tests of the presence within the patient of malaria parasites or their components. Since malaria parasites can be present even in the absence of malaria, and since symptoms of malaria can be manifested even in the absence of malaria parasites, malaria diagnosis raises important issues for the adequate understanding of disease, etiology and diagnosis. One approach to the resolution of these issues adopts a realist view, according to which the needed clarifications will be derived from a careful representation of the entities on the side of the patient which form the ultimate truthmakers for clinical statements. We address a challenge to this realist approach relating to the diagnosis of malaria, and show how this challenge can be resolved by appeal to Basic Formal Ontology (BFO) and to the Ontology for General Medical Science (OGMS) constructed in its terms.
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- This document is licensed to the public under the Creative Commons Attribution 3.0 License
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Ceusters, Werner and Smith, Barry. Malaria Diagnosis and the Plasmodium Life Cycle: the BFO Perspective. Available from Nature Precedings <http://dx.doi.org/10.1038/npre.2009.3960.1> (2009)
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Other versions of this document in Nature Precedings
Version number Document title Date v2 Posted 06 January 2010 Other versions of this document elsewhere on the web
None known.
Werner Ceusters on 05 January 2010 14:36 UTC
This paper is accepted for InterOntology 2010, Tokyo, Feb 27-28, 2010.