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Polyelectrolyte multilayer assembly bearing ketoprofen for transdermal delivery

Rachna Gupta¹, Preeti Yadav¹ & Subhini A. Saraf¹

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1. BBDNITM, Lucknow, India

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Document Type:

Poster

Date:

Received 11 October 2009 07:28 UTC; Posted 12 October 2009

Subjects:

Pharmacology

Tags:

• Multilayered
• Polyelectrolytes
• transdermal
• arthritis
• Microencapsulation.

Abstract:

A novel microencapsulation technology based on layer-by-layer assembly has been extensively studied and used for controlled delivery of drug microcrystal having poor aqueous solubility and low bioavailability. A non-steroidal anti-inflammatory drug ketoprofen (KF)was selected for encapsulation using biodegradable and biocompatible polyions and synergistically the fabricated system was embedded in gel matrix for topical application. Topical application of the drugs at the pathological sites offer potential advantages of delivering the drug directly to the site of action and thus producing high tissue concentrations of the drug.

Presented at:

XVII International conference on Bioencapsulation , Groningen, Netherland, 24 September 2009

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License:

This document is licensed to the public under the Creative Commons Attribution 3.0 License

How to cite this document:

Gupta, Rachna, Yadav, Preeti, and Saraf, Subhini A.. Polyelectrolyte multilayer assembly bearing ketoprofen for transdermal delivery. Available from Nature Precedings <http://dx.doi.org/10.1038/npre.2009.3849.1> (2009)

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