hdl:10101/npre.2009.3635.1
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Hematopoietic Cell Types: Prototype for a Revised Cell Ontology

Alexander D. Diehl1, Alison D. Augustine2, Judith A. Blake1, Lindsay G. Cowell3, Elizabeth S. Gold4, Timothy A. Gondré-Lewis2, Anna Maria Masci3, Terrence F. Meehan1, Penelope A. Morel5, Anastasia Nijnik6, Bjoern Peters7, Bali Pulendran8, Richard H. Scheuermann9, Q. Alison Yao2, Martin S. Zand10 & Christopher J. Mungall11

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  1. The Jackson Laboratory
  2. National Institute of Allergy and Infectious Disease
  3. Duke University Medical Center
  4. Institute for Systems Biology
  5. University of Pittsburgh
  6. University of British Columbia
  7. La Jolla Institute for Allergy and Immunology
  8. Emory University
  9. U.T. Southwestern Medical Center
  10. University of Rochester Medical Center
  11. Lawrence Berkeley Laboratory
Document Type:
Manuscript
Date:
Received 17 August 2009 19:08 UTC; Posted 19 August 2009
Subjects:
Immunology, Bioinformatics
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Abstract:

The Cell Ontology (CL) aims for the representation of in vivo and in vitro cell types from all of biology. Although the CL is a reference ontology of the OBO Foundry, it requires extensive revision to bring it up to current standards for biomedical ontologies, both in its structure and its coverage of various subfields of biology. A recent workshop sponsored by NIAID on hematopoietic cell types in the CL addressed both issues. The section of the ontology dealing with hematopoietic cells was extensively revised, and plans were set for structuring these cell type terms as cross-products with logical definitions built from relationships to external ontologies, such as the Protein Ontology and the Gene Ontology. The methods and improvement to the CL in this area represent a paradigm for improvement of the whole of the ontology over time.

Collection:
International Conference on Biomedical Ontology

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This document is licensed to the public under the Creative Commons Attribution 3.0 License
How to cite this document:

Diehl, Alexander, Augustine, Alison, Blake, Judith, Cowell, Lindsay, Gold, Elizabeth, Gondré-Lewis, Timothy, Masci, Anna Maria, Meehan, Terrence, Morel, Penelope, Nijnik, Anastasia, Peters, Bjoern, Pulendran, Bali, Scheuermann, Richard, Yao, Q. Alison, Zand, Martin, and Mungall, Christopher. Hematopoietic Cell Types: Prototype for a Revised Cell Ontology. Available from Nature Precedings <http://hdl.handle.net/10101/npre.2009.3635.1> (2009)

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