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Towards an Ontological Representation of Resistance: The Case of MRSa

Albert Goldfain¹, Lindsay G. Cowell² & Barry Smith³

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1. Blue Highway, LLC
2. Duke University Medical Center
3. University at Buffalo

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Document Type:

Manuscript

Date:

Received 27 July 2009 19:08 UTC; Posted 27 July 2009

Subjects:

Bioinformatics

Tags:

• ontology
• Infectious disease
• mrsa
• Infectious Disease Ontology consortium
• antiobiotic resistance

Abstract:

This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. Resistance terms from various existing ontologies are examined and found to be either overly narrow, inconsistent, or
otherwise problematic. We propose a more coherent ontological representation using the antibiotic resistance in Methicillin-Resistant Staphylococcus aureus (MRSa) as a case study.

Collection:

International Conference on Biomedical Ontology

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This document is licensed to the public under the Creative Commons Attribution 3.0 License

How to cite this document:

Goldfain, Albert, Cowell, Lindsay, and Smith, Barry. Towards an Ontological Representation of Resistance: The Case of MRSa. Available from Nature Precedings <http://dx.doi.org/10.1038/npre.2009.3474.1> (2009)

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