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Structural Analysis of Polarizing Indels Argues the Root of the Tree of Life is Near the Chloroflexi

Ruben E. Valas¹ and Philip E. Bourne¹

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1. University of California, San Diego

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Document Type:

Poster

Date:

Received 26 May 2009 18:04 UTC; Posted 27 May 2009

Subjects:

Genetics & Genomics, Bioinformatics, Evolutionary Biology

Tags:

• transition analysis
• indel polarization
• root of the tree of life
• LUCA

Abstract:

Determining which branches of the tree of life have derived features narrows down the possible location of the root. Currently the polarization of indels done by Lake et al.^1-5 and the polarizing transitions of Cavalier-Smith⁶ arrive at contradictory positions for the root of the tree. We have analyzed the sequence based indel arguments using protein structure wherever possible. Structure strongly supports some of the polarizations, but in other indels it argues for a different conclusion. We conclude that there is no contradiction between Lake et al. and Cavalier-Smith; the root of the tree of life must be near the Chloroflexi.

Presented at:

2009 CSHL Symposium: Evolution - The Molecular Landscape, 27 May 2009

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License:

This document is licensed to the public under the Creative Commons Attribution 3.0 License

How to cite this document:

Valas, Ruben and Bourne, Philip. Structural Analysis of Polarizing Indels Argues the Root of the Tree of Life is Near the Chloroflexi. Available from Nature Precedings <http://dx.doi.org/10.1038/npre.2009.3290.1> (2009)

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