doi:10.1038/npre.2009.3251.1
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H-InvDB release 6, a comprehensive annotation resource for human genes and transcripts

Chisato Yamasaki1, Katsuhiko Murakami2, Jun-ichi Takeda1, Yoshiharu Sato1, Akiko Noda1, Ryuichi Sakate1, Takuya Habara1, Hajime Nakaoka3, Fusano Todokoro4, Akihiro Matsuya5, Tadashi Imanishi1 & Takashi Gojobori6

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  1. BIRC, AIST
  2. JBIC
  3. JBIC, C's Lab Co.
  4. JBIC, Dynacom Co. Ltd.
  5. JBIC, Hitachi Ltd.
  6. BIRC, AIST, CIB-DDBJ
Document Type:
Poster
Date:
Received 14 May 2009 02:31 UTC; Posted 14 May 2009
Subjects:
Genetics & Genomics, Bioinformatics, Evolutionary Biology
Tags:
Abstract:

H-Invitational Database (H-InvDB; http://www.h-invitational.jp/) is an integrated database of human genes and transcripts. By extensive analyses of all human transcripts, we provide curated annotations of human genes and transcripts that include gene structures, alternative splicing isoforms, non-coding functional RNAs, protein functions, functional domains, sub-cellular localizations, metabolic pathways, protein 3D structure, genetic polymorphisms, relation with diseases, gene expression profiling, molecular evolutionary features, protein-protein interactions (PPIs) and gene families/groups. The latest release of H-InvDB (release 6.0) provide annotation for 219,765 human transcripts in 43,159 human gene clusters based on human FLcDNAs and mRNAs.

H-InvDB consists of two main views, the Transcript view and the Locus view, and six auxiliary databases with web-based viewers; G-integra, H-ANGEL, DiseaseInfo Viewer, Evola, PPI view and Gene Family/Group view. We also provides several data mining tools such as
“Navi search”: consists of 16 search contents each of which includes items for the search condition (http://www.h-invitational.jp/hinv/c-search/hinvNaviTop.jsp), “PANDA”: Priority ANalysis for Disease Association (PANDA) system (http://www.h-invitational.jp/panda/app), H-InvDB now provides web service APIs of SOAP and REST to use H-InvDB data in programs. (http://www.h-invitational.jp/hinv/hws/doc/)

Collection:
3rd International Biocuration Conference
Presented at:
3rd International Biocuration Conference, 16 April 2009

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This document is licensed to the public under the Creative Commons Attribution 3.0 License
How to cite this document:

Yamasaki, Chisato, Murakami, Katsuhiko, Takeda, Jun-ichi, Sato, Yoshiharu, Noda, Akiko, Sakate, Ryuichi, Habara, Takuya, Nakaoka, Hajime, Todokoro, Fusano, Matsuya, Akihiro, Imanishi, Tadashi, and Gojobori, Takashi. H-InvDB release 6, a comprehensive annotation resource for human genes and transcripts. Available from Nature Precedings <http://dx.doi.org/10.1038/npre.2009.3251.1> (2009)

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