3 votes

XML in Motion from Genome to Drug

C. Gopi Mohan¹

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1. Centre for Pharmacoinformatics, National Institute of Pharmaceutical Education and Research (NIPER)

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Document Type:

Manuscript

Date:

Received 28 June 2007 13:33 UTC; Posted 28 June 2007

Subjects:

Chemistry, Bioinformatics

Tags:

• high throughput
• sequence-structure-function relationships
• XML
• databases
• bioinformatics

Abstract:

Information technology (IT) has emerged as a central to the solution of contemporary genomics and drug discovery problems. Researchers involved in genomics, proteomics, transcriptional profiling, high throughput structure determination, and in other sub-disciplines of bioinformatics have direct impact on this IT revolution. As the full genome sequences of many species, data from structural genomics, micro-arrays, and proteomics became available, integration of these data to a common platform require sophisticated bioinformatics tools. Organizing these data into knowledgeable databases and developing appropriate software tools for analyzing the same are going to be major challenges. XML (eXtensible Markup Language) forms the backbone of biological data representation and exchange over the internet, enabling researchers to aggregate data from various heterogeneous data resources. The present article covers a comprehensive idea of the integration of XML on particular type of biological databases mainly dealing with sequence-structure-function relationship and its application towards drug discovery. This e-medical science approach should be applied to other scientific domains and the latest trend in semantic web applications is also highlighted.

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1 comment

Lindenbaum Pierre on 28 June 2007 14:47 UTC

I would have liked to see a citation about LSID and RDF in this review.

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License:

This document is licensed to the public under the Creative Commons Attribution 2.5 License

How to cite this document:

Mohan, C. Gopi. XML in Motion from Genome to Drug . Available from Nature Precedings <http://dx.doi.org/10.1038/npre.2007.287.1> (2007)

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