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Motor Nucleus of the Trigeminal Nerve

Allen Institute for Brain Science¹, Nicholas A. Kostakis¹, Lydia L. Ng¹ & Angela L. Guillozet-Bongaarts¹

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1. Allen Institute for Brain Science

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Document Type:

Manuscript

Date:

Received 15 August 2008 17:30 UTC; Posted 18 August 2008

Subjects:

Genetics & Genomics, Neuroscience

Tags:

• Motor Nucleus of the Trigeminal Nerve
• In-situ hybridization
• Allen Institute for Brain Science
• gene expression
• Pons
• Neuroanatomy

Abstract:

This report contains a summary of expression patterns for genes that are enriched in the motor nucleus of the trigeminal nerve (V) of the pons. All data is derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project. The structure’s location and morphological characteristics in the mouse brain are described using the Nissl data found in the Allen Reference Atlas. Using an established algorithm, the expression values of the motor nucleus of the trigeminal nerve were compared to the values of its larger parent structure, in this case the pons, for the purpose of extracting regionally selective gene expression data. The highest ranking genes were manually curated and verified. 50 genes were then selected and compiled for expression analysis. The experimental data for each gene may be accessed via the links provided; additional data in the sagittal plane may also be accessed using the ABA. Correlations between gene expression in the motor nucleus of the trigeminal nerve and the rest of the brain, across all genes in the coronal dataset (~4300 genes), were derived computationally. A gene ontology table (derived from DAVID Bioinformatics Resources 2007) is also included, highlighting possible functions of the 50 genes selected for this report.

Collection:

Allen Brain Atlas Reports

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License:

This document is licensed to the public under the Creative Commons Attribution 3.0 License

How to cite this document:

for Brain Science, Allen Institute, Kostakis, Nicholas, Ng, Lydia , and Guillozet-Bongaarts, Angela. Motor Nucleus of the Trigeminal Nerve. Available from Nature Precedings <http://dx.doi.org/10.1038/npre.2008.2202.1> (2008)

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