hdl:10101/npre.2008.1431.2
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Phytochemical Approach and Bioanalytical Strategy to Develop Chaperone-Based Medications

Bernd Kastenholz1

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  1. Research Centre Juelich, Institute Phytosphere (ICG-3), Germany

This manuscript is a preprint. A published version is available at:

10.2174/1874091X00802010044 (Peer Reviewed) The Open Biochemistry Journal (2008), 2, 44-48
Document Type:
Manuscript
Date:
Received 08 April 2008 16:45 UTC; Posted 09 April 2008
Subjects:
Chemistry, Pharmacology, Plant Biology
Tags:
Abstract:

Currently, no pharmaceuticals for the etiological treatment of degenerative protein-misfolding diseases (e.g., ALS, Alzheimer’s or prion diseases) are commercially available. Therefore, in this technical note theoretical considerations and practical approaches concerning the development of chaperone-based medications from medicinal plants (e.g., Ginkgo biloba) are reviewed and discussed in detail. Phytochaperones and other agents isolated from medicinal plants are proposed to serve as the general basis of drug development in protein-misfolding diseases.

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Additional information

License:
This document is licensed to the public under the Creative Commons Attribution 3.0 License
How to cite this document:

Kastenholz, Bernd. Phytochemical Approach and Bioanalytical Strategy to Develop Chaperone-Based Medications. Available from Nature Precedings <http://hdl.handle.net/10101/npre.2008.1431.2> (2008)

Version info:

Published version:

10.2174/1874091X00802010044 (Peer Reviewed) The Open Biochemistry Journal (2008), 2, 44-48

Other versions of this document in Nature Precedings

Version number Document title Date
v1 Posted 18 December 2007

Other versions of this document elsewhere on the web

None known.

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